Hampton AlumaSeal™ II Sealing Film and Applicator

Hampton AlumaSeal™ II Sealing Film and Applicator

Applications
Sealing film used to reseal HT format screen kits in polypropylene blocks and plates
Features
Excellent seal
Film conforms to raised chimney wells
Easily pierceable with single or multichannel pipettors and robotic probes
Heat & cold resistant, recommended for temperatures from -80 °C to +120 °C
Certified DNase-, RNase-, and nucleic-acid-free
Less evaporation than clear films
Excellent barrier properties, virtually no reagent evaporation or drying
 Description
A 38 µm soft non-permeable aluminum foil sealing film with strong medical-grade adhesive, AlumaSeal II sealing films eliminate the need for heat-sealing devices or mats during the resealing of reagents in polypropylene deep well blocks. Each sealing film measures 82.6 x 142.9 mm and offers sufficient sealing area for 96 deep well blocks. Length between the perforations with end tabs removed is 125.4 mm. Compared to other aluminum foils, AlumaSeal II has less tendency to roll back on itself when removing the backing paper and it conforms well to the plate during application.AlumaSeal II is a soft, pierceable adhesive film designed for the convenient and rapid sealing of polypropylene deep well blocks. A multiple split backing with two end tabs allows for easy, accurate positioning and secure sealing. The use of an adhesive sealing film minimizes evaporation and helps to prevent well-to-well cross contamination in reagent blocks. AlumaSeal II films are easily pierced by pipettte tips or robotic probes or piercing tools for direct reagent recovery without significant gumming by adhesive.
AlumaSeal™ II Sealing Film and Applicator
AlumaSeal™ II Sealing Film and Applicator

CAT NO NAME DESCRIPTION
HR8-069 AlumaSeal II Sealing Film 100 pack
HR4-413 Film Sealing Paddle 5 pack

Hampton蛋白质结晶捞针(结晶环)18 mm Mounted CryoLoop™

Hampton蛋白质结晶捞针(结晶环)18 mm Mounted CryoLoop™

Applications

Cryocrystallography
Features

Adjustable loop orientation
Synthetic CryoLoop on adjustable stainless steel MicroTube
MicroTube specially engineered with EasySnap notches
20 micron diameter nylon CryoLoop

Description
Similar to the Mounted CryoLoop™ in design and function, the Adjustable Mounted CryoLoop allows one to manipulate and orient the CryoLoop to multiple, unique positions previously unattainable with typical cryo setups. The Adjustable Mounted CryoLoop is a 20 micron diameter synthetic loop mounted inside a malleable stainless steel sleeve, which in turn, is mounted inside the EasySnap MicroTube™.
Using a specially designed L-shaped tool (HR5-902) with a positioning notch, one can manipulate the angle and orientation of the CryoLoop by bending and adjusting the angle of the malleable stainless steel insert which holds the CryoLoop. The Adjustable Mounted CryoLoop may be positioned several times. Note: Repeated manipulation will fatigue the sleeve which can lead to failure of the sleeve. The Adjustable Mounted CryoLoop is designed to work with the CrystalCap System components.
The MicroTube is 24 mm in length and is specially engineered with EasySnap™ notches at the 10, 12, 14, 18, and 21 mm measures. To obtain the desired length of MicroTube, simply snap the MicroTube at the desired length and stake it to the CrystalCap™ Magnetic or CrystalCap™ Copper Magnetic. These nylon loops show minimal diffraction, are thin for fast freezing, strong, and aerodynamic.
Most data collection geometries prefer or require a 22 mm length between the base of the cap and the beam. For a 22 mm overall length using the CrystalCap, CrystalCap ALS, CrystalCap ALS HT and CrystalCap SPINE HT, snap the MicroTube at the second notch from the bottom, creating an 18 mm MicrozTube lenghth and secure to the CrystalCap using epoxy or similar adhesive. For a 22 mm over length using the CrystalCap Copper, CrystalCap Copper HT, CrystalCap ALS Copper HT snap the MicroTube at the fifth notch from the bottom (notch closest to the CryoLoop) and secure to the CrystalCap using epoxy or similar adhesive.
The HR5-902 Tool for Adjustable Mounted CryoLoop is not included with the Adjustable Mounted CryoLoop and must be purchased as a separated item.
18 mm Mounted CryoLoop™ - 20 micron
18 mm Mounted CryoLoop
18 mm Mounted CryoLoop™ - 20 micron
18 mm Mounted CryoLoop properly installed in a CrystalCap Magnetic
18 mm Mounted CryoLoop™ - 20 micron
Crystal in CryoLoop

CAT NO NAME DESCRIPTION
HR4-932 18 mm Mounted CryoLoop – 20 micron 0.025 – 0.05 mm – 25 pack
HR4-945 18 mm Mounted CryoLoop – 20 micron 0.05 – 0.1 mm – 25 pack
HR4-947 18 mm Mounted CryoLoop – 20 micron 0.1 – 0.2 mm – 25 pack
HR4-970 18 mm Mounted CryoLoop – 20 micron 0.2 – 0.3 mm – 25 pack
HR4-971 18 mm Mounted CryoLoop – 20 micron 0.3 – 0.4 mm – 25 pack
HR4-972 18 mm Mounted CryoLoop – 20 micron 0.4 – 0.5 mm – 25 pack
HR4-973 18 mm Mounted CryoLoop – 20 micron 0.5 – 0.7 mm – 25 pack
HR4-974 18 mm Mounted CryoLoop – 20 micron 0.7 – 1.0 mm – 25 pack
HR4-918 18 mm Mounted CryoLoop – 20 micron Sampler – 30 pack (5 of each diameter size 0.1 – 1.0 mm)

Hampton蛋白结晶小瓶和结晶柱底座CrystalCap™

Hampton蛋白结晶小瓶和结晶柱底座CrystalCap™

Applications

Cryocrystallography  低温结晶学
Features

SSRL style sample mount for cryocrystallography
CrystalCap attaches magnetically to CrystalCap Vial and Magnetic Goniometer Base
Conical shape with ledge compatible with SSRL style grippers, auto mounters and sample handlers

Description
The CrystalCap is a magnetic sample mount (also known as a cap, pin or goniometer base) designed for cryocrystallography systems that accept SSRL style sample mounts. The CrystalCap attaches to a magnetic CrystalCap Vial and Magnetic Goniometer Base. The tip of the CrystalCap accepts a Mounted CryoLoop™ or MicroTube™ fitted with a CryoLoop™.
The CrystalCap Vial is a 1.8 ml cryo vial featuring two small vents. A ring magnet is molded into the open end of the vial so that when the cap is positioned in the vial, the ring magnet holds the cap on the vial during cryogenic storage.The HR4-904 CrystalCap Vial does not have a magnet on the bottom of the vial.
The conical shape with ledge is compatible with SSRL style grippers, auto mounters and sample handlers.
Compatible with the following Synchrotron Radiation Beamlines
North & South America
• The Advanced Light Source, Berkeley, California ALS 4.2.2, ALS 11.3.1, ALS 12.2.2, ALS 12.3.2
• The Advanced Photon Source, Argonne, Illinois APS 14-BM-C BioCARS, APS 14-ID-B BioCARS
• Cornell High Energy, Synchrotron Source, Ithaca, New York CHESS A1, CHESS F1
• Canadian Light Source, Saskatchewan, Canada, CLS 08ID-1, CLS 08B1-1
• National Synchrotron Light Source, Upton, New York NSLS X4C
• Stanford Synchrotron Radiation Laboratory, Menlo Park, California SSRL BL7-1, SSRL BL9-1, SSRL BL9-2, SSRL BL11-1, SSRL BL12-2, SSRL BL14-1
Asia & Australia
• Shanghai Synchrotron Radiation Facility, Shanghai, China SSRF BL17U1
• National Synchrotron Radiation Research Center, Taiwan NSRRC BL13B1, NSRRC BL13C1
• Pohang Accelerator Laboratory, Pohang, South Korea PAL 2D, PAL 5C, PAL 7A
• Photon Factory, Tsukuba, Japan PF BL-5A, PF BL-17A, PF AR-NW12A
• Super Photon ring-8 GeV, Japan SPRING-8 BL12B2, SPRING-8 BL24XU, SPRING-8 BL26B1, SPRING-8 BL26B2, SPRING-8 BL32B2, SPRING-8 BL32XU, SPRING-8 BL38B1, SPRING-8 BL41XU, SPRING-8 BL44B2, SPRING-8 BL44XU
CrystalCap™
CrystalCap
CrystalCap™
CrystalCap & Vial
CrystalCap™
CrystalCap
Hampton蛋白结晶小瓶和结晶柱底座 CrystalCap™

CAT NO NAME DESCRIPTION
HR4-733 CrystalCap with Vial – 60 pack
HR4-902 CrystalCap without Vial – 60 pack
HR4-904 CrystalCap Vial Vial only – 30 pack

Hampton AlumaSeal™ II Sealing Film and Applicator

Hampton AlumaSeal™ II Sealing Film and Applicator

Applications
Sealing film used to reseal HT format screen kits in polypropylene blocks and plates
Features
Excellent seal
Film conforms to raised chimney wells
Easily pierceable with single or multichannel pipettors and robotic probes
Heat & cold resistant, recommended for temperatures from -80 °C to +120 °C
Certified DNase-, RNase-, and nucleic-acid-free
Less evaporation than clear films
Excellent barrier properties, virtually no reagent evaporation or drying
 Description
A 38 µm soft non-permeable aluminum foil sealing film with strong medical-grade adhesive, AlumaSeal II sealing films eliminate the need for heat-sealing devices or mats during the resealing of reagents in polypropylene deep well blocks. Each sealing film measures 82.6 x 142.9 mm and offers sufficient sealing area for 96 deep well blocks. Length between the perforations with end tabs removed is 125.4 mm. Compared to other aluminum foils, AlumaSeal II has less tendency to roll back on itself when removing the backing paper and it conforms well to the plate during application.AlumaSeal II is a soft, pierceable adhesive film designed for the convenient and rapid sealing of polypropylene deep well blocks. A multiple split backing with two end tabs allows for easy, accurate positioning and secure sealing. The use of an adhesive sealing film minimizes evaporation and helps to prevent well-to-well cross contamination in reagent blocks. AlumaSeal II films are easily pierced by pipettte tips or robotic probes or piercing tools for direct reagent recovery without significant gumming by adhesive.
AlumaSeal™ II Sealing Film and Applicator
AlumaSeal™ II Sealing Film and Applicator

CAT NO NAME DESCRIPTION
HR8-069 AlumaSeal II Sealing Film 100 pack
HR4-413 Film Sealing Paddle 5 pack

Hampton蛋白结晶工具及仪器

Hampton蛋白结晶工具及仪器
CryoTong™ – Long
ApplicationsCrystal transfer under cryo temperature
FeaturesArtery clamp style closure30 seconds of cryo temperature180 mm length
Description
The CryoTong is a tool used to manually transfer a crystal mounted on a CrystalCap™ from liquid nitrogen to a magnetic base in a goniometer head positioned in a cryogenic stream, and then back to liquid nitrogen. The one-piece, compact CryoTong is available in two lengths. The long CryoTong is approximately 180 mm in overall length. The artery clamp style maintains the CryoTong in the closed position until the clamp is squeezed, which opens the opposing heads. The heads are non-magnetic stainless steel. The handle is magnetic stainless steel. The inside of the head is machined to closely surround the CrystalCap with loop and crystal in place. A small retaining lip is machined into the lower portion of the head to prevent the CrystalCap from slipping out of the CryoTong when the tool is in the closed position. The CryoTong can maintain the temperature of the crystal at -160°C for up to 30 seconds during room temperature crystal transfers. Choose the proper CryoTong size based upon the pin length required by the configuration of the x-ray data collection hardware used. The 18 mm CryoTong (HR5-112) is to be used with the CrystalCap HT and any other CrystalCap configured for 18 mm.HR5-114 Long CryoTong 18 mm, 180° features the head in alignment with the handle of the CryoTong.

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Vial Clamp™ – Straight
ApplicationsVial support and manipulation
FeaturesStraight end tipHemostat style closureDescription
The Vial Clamp™ – Straight is a chrome plated, hemostat style tool. It has a tip shaped to hold the storage vial of all the CrystalCap Systems™ straight when the clamp is closed. The clamp can be locked using the hemostat style closure. This clamp makes it easy to dip the storage vial into liquid nitrogen for crystal storage. The complete length of the clamp is straight, with an overall length of 195 mm. When the vial is placed in the clamp, the length of it is positioned perpendicular, 90° to the length of the clamp.
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CrystalWand™ Magnetic
ApplicationsCrystalCap Magnetic & CrystalCap Copper Magnetic handling toolDescription
The CrystalWand Magnetic is designed to be used exclusively with the CrystalCap Magnetic, CrystalCap Copper Magnetic, and CrystalCap HT systems during transfer of the caps from the vial to the goniometer head and from the goniometer to the vial. The 6 1/2” (165 mm) long chrome plated steel wand features a plastic housing enclosing a spring tensioned plunger that when depressed, moves a non-magnetic steel platform away from the magnet housed in the end of the wand. This causes the steel CrystalCap to detach from the wand and be placed readily into the vial or the CryoTong™. When the platform is retracted, the wand securely holds the steel CrystalCap Magnetic. The CrystalWand Magnetic 45° (McMiken Tool) offers the same functionality but is bent at a 45° angle at approximately 2.5 cm from the magnet end.HR4-729 CrystalWand Magnetic, StraightHR4-315 CrystalWand Magnetic, 45° (McMiken Tool)
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Vial Clamp™ – Curved
ApplicationsVial support & manipulation
FeaturesCurved end tipHemostat style closureDescription
The Vial Clamp – Curved is a chrome plated, hemostat style tool. It has a tip shaped to hold the storage vial of all the CrystalCap Systems at an angle when the clamp is closed. The clamp can be locked using the hemostat style closure. The end of the clamp, where the vial is held, is curved at either a 45°/135° or 110°/ 70° angle. When the vial is placed in the clamp, the length of it is positioned to the clamp at either of those same angles. The overall length of each clamp is the same, 195 mm.HR4-671 Vial Clamp – Curved 45°/135°HR4-672 Vial Clamp – Curved 110°/70°
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CrystalCap™ Holder
pplicationsCrystalCap support inside stainless steel dewars
FeaturesAdjustable heightSupports up to 8 CrystalCaps15 ml vial position for liquid propane500 and 1,000 ml versionsDescription
CrystalCap Holders are convenient stands for holding all CrystalCap™ systems in liquid nitrogen dewars during crystal cryogenic procedures. Available in two sizes. Both holders feature spring-clips to secure the CrystalCap Vials in the holder. Both stands have 3 inches of adjustable Z (height) which allows one to raise or lower the CrystalCaps to the appropriate height, depending upon the liquid nitrogen level in the dewar. Each holder is supplied with a socket driver for height adjustment.500 ml version holds five CrystalCaps, two 15 ml vials (for liquid propane procedures) and fits into the 500 ml dewar. 1,000 ml version holds eight CrystalCaps, two 15 ml vials (for liquid propane procedures) and fits into the 1,000 ml dewar.HR4-707 CrystalCap Holder – 500 ml
HR4-706  Replacement Height Adjustment Tool
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Hampton PEG/Ion • PEG/Ion 2 • PEG/Ion HT

Hampton PEG/Ion • PEG/Ion 2 • PEG/Ion HT

Applications
  Primary or secondary, polymer, salt and pH matrix crystallization screen for biological macromolecules
Features

Developed at Hampton Research
PEG/Ion is a sparse matrix profile of anions and cations in the presence of monodisperse Polyethylene glycol 3,350 over pH 4.5 – 9.2
PEG/Ion 2 screens a complete profile of titrated organic acids at varying pH levels (3.7 – 8.8) in the presence of monodisperse PEG 3,350
PEG/Ion HT combines PEG/Ion and PEG/Ion 2 in a single 96 Deep Well block
 Description

PEG/Ion, developed by Hampton Research, is a crystallization screen designed to evaluate monodisperse, high purity Polyethylene glycol 3,350 and 48 unique salts representing a very complete range of anions and cations frequently used in the crystallization of biological macromolecules. The primary screening variables are PEG, ion type, ionic strength, and pH. More than 60% of the published crystallizations utilized PEG as a primary crystallization reagent and in approximately 50% of those reports, the PEG was combined with an ion as a secondary crystallization reagent. PEG/Ion reagents are formulated without a buffer and are not pH titrated.
PEG/Ion 2 is an extension to the fundamental crystallization strategy in PEG/Ion. PEG/Ion 2 reagents cover the monodisperse, high purity Polyethylene glycol 3,350 and an array of neutralized and pH adjusted organic acids, multivalent ions, a novel Citrate BIS-TRIS propane buffer system and pH (4 – 8.8). The formulation of PEG/Ion 2 was developed at Hampton Research. Each of the 48 reagents in PEG/Ion 2 contains PEG 3,350 as the polymer (precipitant). The concentration of PEG is varied from 12% w/v to 20% w/v depending upon the type and concentration of buffer/salt paired with the polymer. Thirteen of the forty-eight PEG/Ion 2 reagents contain a separate buffer component. The remaining PEG/Ion 2 reagents are buffered by the titrated organic acid salt. Six of these thirteen conditions feature a novel Citric acid BIS-TRIS propane (CBTP) buffer. The CBTP buffer uses Citric acid and BIS-TRIS propane as the acid base pair to create a two component buffer system effective across pH 2.5 to 9.5. The ratio of Citric acid to BIS-TRIS propane determines the solution pH. Thirty-five of the forty-eight PEG/Ion 2 reagents contain a neutralized or pH adjusted organic acid in the presence of the polymer. Neutralized organic acids are highly effective crystallization salts.1 Four PEG/Ion 2 reagents feature polyvalent cations. Two of these reagents contain cation mixes, saving sample by screening six different cations with only two reagents. Tryptone, a casein digest combinatorial library of peptides, is included in PEG/Ion 2. PEG/Ion 2 reagents 1-30, 42, 45-47 are formulated without a buffer and are not pH titrated.
PEG/Ion contains 48 unique reagents, 10 ml each.
PEG/Ion 2 contains 48 unique reagents, 10 ml each.
PEG/Ion HT contains 1 ml of each reagent from PEG/Ion and PEG/Ion 2 in a single Deep Well block format.
Ready-to-use reagents are sterile filtered and formulated with ultra-pure Type 1 water, using the highest purity salts, polymers, organics and buffers. Individual reagents are available through the Hampton Research Custom Shop.
PEG/Ion • PEG/Ion 2 • PEG/Ion HT

PEG/Ion • PEG/Ion 2 • PEG/Ion HT

Hampton结晶用缓冲盐试剂盒– SaltRx

Hampton结晶用缓冲盐试剂盒– SaltRx
SaltRx 1 • SaltRx 2 • SaltRx HT

Applications
Primary or secondary, salt and pH matrix crystallization screen for biological macromolecules
Features

Salt versus pH matrix crystallization screen
Samples pH 4 to 9
22 unique salts versus salt concentration and pH
Compatible with microbatch, vapor diffusion, liquid & gel diffusion methods
Tube or Deep Well block format
Preformulated, ready to screen
Developed at Hampton Research
All salts and buffers in screen readily available as Optimize™ reagents for reproducing and optimizing crystals
Individual reagents available through the Hampton Research Custom Shop
 Description
SaltRx was developed by Hampton Research as a primary and secondary, salt and pH based crystallization screen for biological macromolecules. Salt is the only primary crystallization reagent (precipitant) utilized. Based on a design of 96 conditions, the screen evaluates a broad portfolio of crystallization salts of varying concentration and pH. The selection, concentration, and pH of the salts were determined by data mining the BMCD1 and other crystallization databases, crystallization reports in the literature, and internal crystallization trials performed at Hampton Research. Based on this analysis, up to 35% of protein crystallizations involve salt as the primary crystallization reagent. SaltRx can be used as a primary crystallization screen when salt, ionic strength and pH are desired or suspected as appropriate crystallization variables. It is also useful as a secondary screen when salt only reagents/conditions from screens such as Index™, Crystal Screen™, and Grid Screen™ produce crystals and when further screening for additional salt conditions or optimization is desired. Since this screen does not contain volatile organics, it is compatible with microbatch, vapor diffusion, liquid and gel diffusion crystallization methods. SaltRx may also be used for dialysis crystallization in conjunction with Dialysis Buttons™.The original SaltRx kit (HR2-108) contained 96 unique reagents, 10 ml each. This kit has been discontinued and converted into two 48 reagent based kits, SaltRx 1 and SaltRx 2, available separately, which when used together are identical to the original SaltRx.SaltRx 1 contains 48 unique reagents, 10 ml each. SaltRx 1 contains reagents 1-48 of the original SaltRx 96 reagent kit.Salt Rx 2 contains 48 unique reagents, 10 ml each. SaltRx 2 contains reagent 49-96 of the original SaltRx 96 reagent kit.SaltRx HT contains the 96 SaltRx 1 and SaltRx 2 reagents in a single Deep Well block format.Ready-to-use reagents are sterile filtered and formulated with ultra-pure Type 1 water, using the highest purity salts, polymers, organics and buffers. Individual reagents are available through the Hampton Research Custom Shop.
Measured pH range of kit is 4.1 to 9.0 at 25°C
Average measured pH of kit is 6.9 at 25°C
Median measured pH of kit is 7.3 at 25°C
Mode measured pH of kit is 7.4 at 25°C
CAT NO NAME DESCRIPTION
HR2-136 SaltRx HT 1 ml, Deep Well block format
HR2-107 SaltRx 1 10 ml, tube format
HR2-109 SaltRx 2 10 ml, tube format

Hampton GRAS 5 • GRAS 6 Screens

Hampton GRAS 5 • GRAS 6 Screens
Applications
 GRAS reagent crystallization screen for proteins, including monoclonal antibodies, where Polyethylene glycol is the primary reagent, sampling pH 4.5 to 10
. Identify GRAS based reagents that promote crystallization of biotherapeutics for bioprocess, bioformulation, and continuous flow manufacturing applications
Features

Developed at Hampton Research
Generally Recognized As Safe reagent formulation
Samples pH 4.5 to 10; 8 unique buffers
Primary crystallization reagent:

GRAS 5: PEG 300, 400, MME 550, & 600
GRAS 6: PEG 1,000, MME 2,000, 3,350 & 4,000

 

Vapor diffusion, microbatch, free interface diffusion
Reagents soluble between 4°C and 30°C

Description

GRAS Screen™ 5 and 6 were developed by Hampton Research for the crystallization of proteins, including monoclonal antibodies. Each of the chemicals in GRAS Screen 5 and 6 has been used under one or more of the following categories. As (1) a Generally Recognized As Safe (GRAS) substance, (2) a pharmaceutical excipient, (3) a normal physiological constituent, (4) a metabolic byproduct, and/or (5) a Everything Added to Food in the United States (EAFUS) substance.
GRAS Screen 5 samples four low molecular weight Polyethylene glycols (300, 400, MME 550, and 600) at three concentrations versus eight unique buffers encompassing pH 4.5 to 10. GRAS Screen 5 is supplied in a 96 Deep Well block format and is compatible with robotic and multi-channel pipet liquid handling systems. GRAS Screen 5 is compatible with vapor diffusion, free interface diffusion, and microbatch crystallization methods. For research use only.
GRAS Screen 6 samples four medium molecular weight Polyethylene glycols (1,000, MME 2,000, 3,350, & 4,000) at three concentrations versus eight unique buffers encompassing pH 4.5 to 10. GRAS Screen 6 is supplied in a 96 Deep Well block format and is compatible with robotic and multi-channel pipet liquid handling systems. GRAS Screen 6 is compatible with vapor diffusion, free interface diffusion, and microbatch crystallization methods. For research use only.

Hampton GRAS 1 • GRAS 2 Screens

Hampton GRAS 1 • GRAS 2 Screens

stallization screen for proteins, including monoclonal antibodies, where Polyethylene glycol is the primary, and Salt the secondary reagent, sampling pH 4-9
GRAS 1 • GRAS 2 ScreensGRAS 1 • GRAS 2 Screens Identify GRAS based reagents that promote crystallization of biotherapeutics for bioprocess, bioformulation, and continuous flow manufacturing applications
Features

Developed at Hampton Research
Generally Recognized As Safe reagent formulation
Samples pH 4.0 – 9.0 without an added buffer
Primary crystallization reagent:

GRAS Screen 1: PEG 300, 400, MME 550, & 600
GRAS Screen 2: PEG 1,000, MME 2,000, 3,350 & 4,000
Secondary crystallization reagent:

24 unique salts
Compatible with Vapor diffusion, microbatch, free interface diffusion
Reagents soluble between 4°C and 30°C

Description
GRAS Screen™ 1 and GRAS Screen™ 2 were developed by Hampton Research for the crystallization of proteins, including monoclonal antibodies. Each of the chemicals in GRAS Screen 1 and 2 have been used under one or more of the following categories. As (1) a Generally Recognized As Safe (GRAS) substance, (2) a pharmaceutical excipient, (3) a normal physiological constituent, (4) a metabolic byproduct, and/or (5) a Everything Added to Food in the United States (EAFUS) substance.
GRAS Screen 1 samples four low molecular weight Polyethylene glycols (300, 400, MME 550, and 600) versus twenty-four salts, encompassing pH 4-9. GRAS Screen 1 is supplied in a 96 Deep Well block format and is compatible with robotic and multi-channel pipet liquid handling systems. GRAS Screen 1 is compatible with vapor diffusion, free interface diffusion, and microbatch crystallization methods. For research use only.
GRAS Screen 2 samples four medium molecular weight Polyethylene glycols (1,000, MME 2,000, 3,350, & 4,000) versus twenty-four salts, encompassing pH 4-9. GRAS Screen 2 is supplied in a 96 Deep Well block format and is compatible with robotic and multi-channel pipet liquid handling systems. GRAS Screen 2 is compatible with vapor diffusion, free interface diffusion, and microbatch crystallization methods. For research use only.

CAT NO NAME DESCRIPTION
HR2-451 GRAS Screen 1 1 ml, Deep Well block format
Price Quantity
$245.00
CAT NO NAME DESCRIPTION
HR2-452 GRAS Screen 2 1 ml, Deep Well block format
Price Quantity
$245.00

Hampton AlumaSeal™ II Sealing Film and Applicator

Hampton AlumaSeal™ II Sealing Film and Applicator

Applications
Sealing film used to reseal HT format screen kits in polypropylene blocks and plates
Features
Excellent seal
Film conforms to raised chimney wells
Easily pierceable with single or multichannel pipettors and robotic probes
Heat & cold resistant, recommended for temperatures from -80 °C to +120 °C
Certified DNase-, RNase-, and nucleic-acid-free
Less evaporation than clear films
Excellent barrier properties, virtually no reagent evaporation or drying
 Description
A 38 µm soft non-permeable aluminum foil sealing film with strong medical-grade adhesive, AlumaSeal II sealing films eliminate the need for heat-sealing devices or mats during the resealing of reagents in polypropylene deep well blocks. Each sealing film measures 82.6 x 142.9 mm and offers sufficient sealing area for 96 deep well blocks. Length between the perforations with end tabs removed is 125.4 mm. Compared to other aluminum foils, AlumaSeal II has less tendency to roll back on itself when removing the backing paper and it conforms well to the plate during application.AlumaSeal II is a soft, pierceable adhesive film designed for the convenient and rapid sealing of polypropylene deep well blocks. A multiple split backing with two end tabs allows for easy, accurate positioning and secure sealing. The use of an adhesive sealing film minimizes evaporation and helps to prevent well-to-well cross contamination in reagent blocks. AlumaSeal II films are easily pierced by pipettte tips or robotic probes or piercing tools for direct reagent recovery without significant gumming by adhesive.
AlumaSeal™ II Sealing Film and Applicator
AlumaSeal™ II Sealing Film and Applicator

CAT NO NAME DESCRIPTION
HR8-069 AlumaSeal II Sealing Film 100 pack
HR4-413 Film Sealing Paddle 5 pack

Hampton Polyethylene glycol 4,000

Hampton Polyethylene glycol 4,000

Applications
Crystallization grade Polyethylene glycol for formulating screens or for optimizatio
Features
Sterile filtered solution
Formulated in Type 1+ ultrapure water: 18.2 megaohm-cm resistivity at 25°C, < 5 ppb Total Organic Carbon, bacteria free (<1 Bacteria (CFU/ml)), pyrogen free (<0.03 Endotoxin (EU/ml)), RNase-free (< 0.01 ng/mL) and DNase-free (< 4 pg/µL)

Description
Polyethylene glycol 4,000
Synonym: PEG 4,000
H(OCH2CH2)nOH
Mr 3,500-4,500
CAS Number [25322-68-3]
EC Number 500-038-2
Merck 14,7568
RTECS TQ3500000
MDL Number MFCD00081839
PubChem Substance ID 24890217
Melting point (Starting Material) 58.0-61.0°C
Aldehyde None detected
Peroxide None detected

HR2-529 Measured pH range: 6.9 – 9.5 at 25°C
HR2-529 Measured Conductivity Range: 35.3 – 46.9 µS/cm at 25°C
HR2-529 Measured Refractive Index Range: 1.40172 – 1.40279 at 20°C

CAT NO NAME DESCRIPTION
HR2-605 Polyethylene glycol 4,000 Flake – 500 g
HR2-529 Polyethylene glycol 4,000 50% w/v solution – 200 ml

Hampton蛋白结晶小瓶和结晶柱底座CrystalCap™

Hampton蛋白结晶小瓶和结晶柱底座CrystalCap™

Applications

Cryocrystallography  低温结晶学
Features

SSRL style sample mount for cryocrystallography
CrystalCap attaches magnetically to CrystalCap Vial and Magnetic Goniometer Base
Conical shape with ledge compatible with SSRL style grippers, auto mounters and sample handlers

Description
The CrystalCap is a magnetic sample mount (also known as a cap, pin or goniometer base) designed for cryocrystallography systems that accept SSRL style sample mounts. The CrystalCap attaches to a magnetic CrystalCap Vial and Magnetic Goniometer Base. The tip of the CrystalCap accepts a Mounted CryoLoop™ or MicroTube™ fitted with a CryoLoop™.
The CrystalCap Vial is a 1.8 ml cryo vial featuring two small vents. A ring magnet is molded into the open end of the vial so that when the cap is positioned in the vial, the ring magnet holds the cap on the vial during cryogenic storage.The HR4-904 CrystalCap Vial does not have a magnet on the bottom of the vial.
The conical shape with ledge is compatible with SSRL style grippers, auto mounters and sample handlers.
Compatible with the following Synchrotron Radiation Beamlines
North & South America
• The Advanced Light Source, Berkeley, California ALS 4.2.2, ALS 11.3.1, ALS 12.2.2, ALS 12.3.2
• The Advanced Photon Source, Argonne, Illinois APS 14-BM-C BioCARS, APS 14-ID-B BioCARS
• Cornell High Energy, Synchrotron Source, Ithaca, New York CHESS A1, CHESS F1
• Canadian Light Source, Saskatchewan, Canada, CLS 08ID-1, CLS 08B1-1
• National Synchrotron Light Source, Upton, New York NSLS X4C
• Stanford Synchrotron Radiation Laboratory, Menlo Park, California SSRL BL7-1, SSRL BL9-1, SSRL BL9-2, SSRL BL11-1, SSRL BL12-2, SSRL BL14-1
Asia & Australia
• Shanghai Synchrotron Radiation Facility, Shanghai, China SSRF BL17U1
• National Synchrotron Radiation Research Center, Taiwan NSRRC BL13B1, NSRRC BL13C1
• Pohang Accelerator Laboratory, Pohang, South Korea PAL 2D, PAL 5C, PAL 7A
• Photon Factory, Tsukuba, Japan PF BL-5A, PF BL-17A, PF AR-NW12A
• Super Photon ring-8 GeV, Japan SPRING-8 BL12B2, SPRING-8 BL24XU, SPRING-8 BL26B1, SPRING-8 BL26B2, SPRING-8 BL32B2, SPRING-8 BL32XU, SPRING-8 BL38B1, SPRING-8 BL41XU, SPRING-8 BL44B2, SPRING-8 BL44XU
CrystalCap™
CrystalCap
CrystalCap™
CrystalCap & Vial
CrystalCap™
CrystalCap
Hampton蛋白结晶小瓶和结晶柱底座 CrystalCap™

CAT NO NAME DESCRIPTION
HR4-733 CrystalCap with Vial – 60 pack
HR4-902 CrystalCap without Vial – 60 pack
HR4-904 CrystalCap Vial Vial only – 30 pack

Hampton蛋白结晶产品目录

Hampton蛋白结晶产品目录

产品编号 中文品名 英文品名
HR4-126 11 刀片替换装 Replacement #11 Blade
HR4-904 CrystalCap Magnetic Vial CrystalCap™, Vial only
HR4-729 CrystalWand Magnetic, Straight CrystalWand™ Magnetic, Straigh
HR4-837 Micro-Tools II Set Micro-Tools II™ Set
HR4-811 Micro-Tools Set Micro-Tools™ Set
HR3-172 VDX 24孔板,带密封剂 VDX™ Plate, with sealant
HR4-902 带磁力底座 CrystalCap™, without Vial
HR4-733 带磁力底座 CrystalCap™, with Vial
HR4-745 带铜管磁力底座 CrystalCap™ Copper 18 mm, with
HR4-708 冻存套 CryoSleeve™
HR3-217 硅化方形盖玻片22mmx0.22mm 22 mm x 0.22 mm Siliconized Sq
HR4-671 夹钳-弯 Vial Clamp™ – Curved, 45°/135°
HR4-670 夹钳-直 Vial Clamp™ – Straight
HR4-316 Super Glue
HR4-506 胶带 3 inch wide x 55 yard Crystal
HR3-083 结晶板 2孔 MRC 2 Well Crystallization Pla
HR3-125 结晶板 3孔 3 Well Crystallization Plate (
HR4-217 晶体探针 Crystal Probe
HR4-662 泡沫保温瓶 Spearlab Cryogenic Foam Dewar
HR4-673 泡沫保温瓶 Spearlab Cryogenic Foam Dewar
HR4-674 泡沫保温瓶 Spearlab Cryogenic Foam Dewar
HR4-675 泡沫保温瓶 Spearlab Cryogenic Foam Dewar
HR1-008 液氮罐 CX100 (含运输箱) CX100 Cryo-Express Dry Shipper
HR2-912-37   Crystal Screen 2™ #37
HR2-501   50% v/v Jeffamine® M-600® pH 7
HR2-509   1.0 M BICINE
HR2-517   100% Polyethylene glycol 300
HR2-523   50% w/v Polyethylene glycol 1,
HR2-525   50% w/v Polyethylene glycol 1,
HR2-529   50% w/v Polyethylene glycol 4,
HR2-533   50% w/v Polyethylene glycol 6,
HR2-537   1.0 M Magnesium formate dihydr
HR2-541   3.5 M Ammonium sulfate
HR2-545   2.0 M Lithium sulfate monohydr
HR2-547   7.0 M Sodium formate
HR2-549   1.6 M Sodium citrate tribasic
HR2-551   4.0 M Sodium phosphate monobas
HR2-557   2.0 M Calcium chloride dihydra
HR2-563   1.0 M Zinc acetate dihydrate
HR2-102   StockOptions™ Hepes
HR2-103   StockOptions™ Bis-Tris Propane
HR2-104   StockOptions™ Citric Acid
HR2-106   StockOptions™ Bis-Tris
HR2-107   SaltRx™ 1
HR2-109   SaltRx™ 2
HR2-110   Crystal Screen™
HR2-112   Crystal Screen 2™
HR2-114   MembFac™
HR2-116   Natrix™
HR2-117   Natrix™ 2
HR2-118   Nucleic Acid Mini Screen™
HR2-126   PEG/Ion Screen™
HR2-235   StockOptions™ Sodium Citrate
HR2-237   StockOptions™ Tris Hydrochlori
HR2-239   StockOptions™ Sodium Cacodylat
HR2-241   StockOptions™ pH
HR2-245   StockOptions™ Salt
HR2-249   StockOptions™ Succinic Acid
HR2-320   Seed Bead™
HR2-406   Detergent Screen HT™
HR2-428   Additive Screen™
HR2-434   Reductive Alylation Kit
HR2-442   Heavy Atom Screen™ Pt
HR2-444   Heavy Atom Screen™ Au
HR2-446   Heavy Atom Screen™ Hg
HR2-448   Heavy Atom Screen M1™
HR2-450   Heavy Atom Screen M2™
HR2-082   PEGRx™ 1
HR2-084   PEGRx™ 2
HR2-096   Silver Bullets™
HR2-098   PEG/Ion 2 Screen™
HR4-315   CrystalWand™ Magnetic, 45° McM
HR4-350   Large Applicator (200 & 350 µl
HR4-625   Mounted CryoLoop™ – 20 micron,
HR4-637   CryoTong™ 18 mm (standard 110
HR4-709   CryoCane™ 5 Vial Holder
HR4-711   CryoCane™ 6 Vial Holder
HR2-211   Grid Screen™ Ammonium Sulfate
HR2-213   Grid Screen™ PEG 6000
HR2-227   StockOptions™ Polymer
HR2-233   StockOptions™ Sodium Acetate
HR4-931   CryoLoop™ – 20 micron, 0.2 – 0
HR4-945   Mounted CryoLoop™ – 20 micron,
HR4-947   Mounted CryoLoop™ – 20 micron,
HR4-953   Mounted CryoLoop™ Sampler – 20
HR4-955   Mounted CryoLoop™ – 20 micron,
HR4-957   Mounted CryoLoop™ – 20 micron,
HR4-959   Mounted CryoLoop™ – 20 micron,
HR4-961   Mounted CryoLoop™ – 20 micron,
HR4-963   Mounted CryoLoop™ – 20 micron,
HR4-970   Mounted CryoLoop™ – 20 micron,
HR4-971   Mounted CryoLoop™ – 20 micron,
HR4-989   CryoLoop™ – 10 micron, 0.3 – 0
HR2-128   Crystal Screen Lite™
HR2-138   Additive Screen HT™
HR2-140   PCT™ – Pre-Crystallization T
HR4-313   Mounted CryoLoop™ – 20 micron,
HR2-601   100% Polyethylene glycol 200
HR2-607   50% w/v Polyethylene glycol 10
HR2-609   30% w/v Polyethylene glycol 20
HR2-611   100% Polyethylene glycol monom
HR2-613   50% w/v Polyethylene glycol mo
HR2-615   50% w/v Polyethylene glycol mo
HR2-625   6.0 M 1,6-Hexanediol
HR2-637   5.0 M Sodium chloride
HR2-723   1.0 M BICINE pH 9.0
HR2-755   100% Tacsimate™ pH 7.0
HR2-761   3.0 M DL-Malic acid pH 7.0
HR2-801   TCEP hydrochloride
HR2-821   2.0 M Magnesium sulfate heptah
HR2-829   100% Tacsimate™ pH 8.0
HR2-857   4.0 M TMAO
HR2-859   100% Polyethylene glycol 600
HR2-910-08   Crystal Screen™ #08
HR2-144   Index™
HR4-993   Mounted CryoLoop™ Sampler – 10
HR4-995   Mounted CryoLoop™ – 10 micron,
HR4-999   Mounted CryoLoop™ – 10 micron,
HR6-146   1.0 mm Quartz Capillary
HR8-034   Cryo Puck Carrier
HR8-035   Porcupine Push Tool
HR8-036   Puck Wand
HR8-037   Cryo Puck Base Removal Platfor
HR8-038   Angled Cryo Puck Tong
HR8-039   Cryo Puck Dewar Loading Tool
HR8-114   CrystalCap HT™, Vial only
HR8-133   Seeding Tool
HR8-173   CrystalCap™ Copper HT, 0.025 –
HR8-174   CrystalCap™ Copper HT, 0.05 –
HR8-175   CrystalCap™ Copper HT, 0.1 – 0
HR8-176   CrystalCap™ Copper HT, 0.2 – 0
HR2-575   1.0 M Sodium cacodylate trihyd
HR2-581   1.0 M Hydrochloric acid

Hampton蛋白质结晶捞针(结晶环)18 mm Mounted CryoLoop™

Hampton蛋白质结晶捞针(结晶环)18 mm Mounted CryoLoop™

Applications

Cryocrystallography
Features

Adjustable loop orientation
Synthetic CryoLoop on adjustable stainless steel MicroTube
MicroTube specially engineered with EasySnap notches
20 micron diameter nylon CryoLoop

Description
Similar to the Mounted CryoLoop™ in design and function, the Adjustable Mounted CryoLoop allows one to manipulate and orient the CryoLoop to multiple, unique positions previously unattainable with typical cryo setups. The Adjustable Mounted CryoLoop is a 20 micron diameter synthetic loop mounted inside a malleable stainless steel sleeve, which in turn, is mounted inside the EasySnap MicroTube™.
Using a specially designed L-shaped tool (HR5-902) with a positioning notch, one can manipulate the angle and orientation of the CryoLoop by bending and adjusting the angle of the malleable stainless steel insert which holds the CryoLoop. The Adjustable Mounted CryoLoop may be positioned several times. Note: Repeated manipulation will fatigue the sleeve which can lead to failure of the sleeve. The Adjustable Mounted CryoLoop is designed to work with the CrystalCap System components.
The MicroTube is 24 mm in length and is specially engineered with EasySnap™ notches at the 10, 12, 14, 18, and 21 mm measures. To obtain the desired length of MicroTube, simply snap the MicroTube at the desired length and stake it to the CrystalCap™ Magnetic or CrystalCap™ Copper Magnetic. These nylon loops show minimal diffraction, are thin for fast freezing, strong, and aerodynamic.
Most data collection geometries prefer or require a 22 mm length between the base of the cap and the beam. For a 22 mm overall length using the CrystalCap, CrystalCap ALS, CrystalCap ALS HT and CrystalCap SPINE HT, snap the MicroTube at the second notch from the bottom, creating an 18 mm MicrozTube lenghth and secure to the CrystalCap using epoxy or similar adhesive. For a 22 mm over length using the CrystalCap Copper, CrystalCap Copper HT, CrystalCap ALS Copper HT snap the MicroTube at the fifth notch from the bottom (notch closest to the CryoLoop) and secure to the CrystalCap using epoxy or similar adhesive.
The HR5-902 Tool for Adjustable Mounted CryoLoop is not included with the Adjustable Mounted CryoLoop and must be purchased as a separated item.
18 mm Mounted CryoLoop™ - 20 micron
18 mm Mounted CryoLoop
18 mm Mounted CryoLoop™ - 20 micron
18 mm Mounted CryoLoop properly installed in a CrystalCap Magnetic
18 mm Mounted CryoLoop™ - 20 micron
Crystal in CryoLoop

CAT NO NAME DESCRIPTION
HR4-932 18 mm Mounted CryoLoop – 20 micron 0.025 – 0.05 mm – 25 pack
HR4-945 18 mm Mounted CryoLoop – 20 micron 0.05 – 0.1 mm – 25 pack
HR4-947 18 mm Mounted CryoLoop – 20 micron 0.1 – 0.2 mm – 25 pack
HR4-970 18 mm Mounted CryoLoop – 20 micron 0.2 – 0.3 mm – 25 pack
HR4-971 18 mm Mounted CryoLoop – 20 micron 0.3 – 0.4 mm – 25 pack
HR4-972 18 mm Mounted CryoLoop – 20 micron 0.4 – 0.5 mm – 25 pack
HR4-973 18 mm Mounted CryoLoop – 20 micron 0.5 – 0.7 mm – 25 pack
HR4-974 18 mm Mounted CryoLoop – 20 micron 0.7 – 1.0 mm – 25 pack
HR4-918 18 mm Mounted CryoLoop – 20 micron Sampler – 30 pack (5 of each diameter size 0.1 – 1.0 mm)

Hampton 蛋白结晶优化试剂 Optimization Screens

Hampton 蛋白结晶优化试剂 Optimization Screens

1、Solubility & Stability Screen  蛋白特异性试剂优化溶解性和稳定性
Protein specific agents for optimization of solubility & stability  
2、Solubility & Stability Screen 2   离子缓冲液
Buffer, pH & ionic strength screen for optimization of solubility & stability
3、Slice pH    PH缓冲液
pH & buffer screen for optimization of crystals or sample solubility & stability
4、Additive Screen  96孔板添加剂试剂盒
96 compound screen for optimization of crystal size & quality
5、Silver Bullets • Silver Bullets Bio
Small molecule additive screen for optimization of crystal size & quality
6、Detergent Screen
Detergent screen for optimization of crystals or sample solubility & stability
7、Ionic Liquid Screen
Ionic liquid additive screen for optimization of crystal size & quality
8、StockOptions Buffer Kits
Titrated buffer sets for optimization of crystals or sample solubility & stability
9、StockOptions Polymer
n of crystal size & quality
10、StockOptions Salt
Salt reagent kit for optimization of crystal size & qualit
11、Polymer reagent kit for optimizatioy
Proti-Ace
In situ proteolysis kit protein for crystallization screening & optimization
12、Reductive Alkylation
Reductive alkylation kit for crystallization screening & optimization
13、Silica Hydrogel Kit
pH neutral silica hydrogel matrix crystallization
14、Low Melting Agarose
Agarose gel matrix crystallization
15、CryoPro
Water soluble cryoprotectant reagent set
16、Heavy Atom Screens
Heavy atom kits for multiple isomorphous replacement
17、I3C Phasing Kit
Produce heavy atom derivative of biological macromolecules for phasing