Himedia Media for Anaerobes  厌氧菌培养基

Himedia Media for Anaerobes  厌氧菌培养基
上海金畔生物科技有限公司,作为HiMedai公司在中国的代理商,在微生物培养和检测领域,会一如既往地为您带来优质的服务。
Himedia代理,欢迎新老客户访问Himedia官网或者咨询我们获取更多有关产品信息。
Veterinary > Media for Anaerobes

Media for anaerobes such as Clostridium spp. and others responsible for various diseases in veterinary animals are offered by HiMedia. Reinforced Clostridial Agar, SPS agar, Anaerobic Thioglycollate Medium Base are some of the medium used for their isolation and cultivation.
厌氧菌的培养基,如梭菌。其他对兽医疾病负责的人则由Himedia提供。强化梭菌琼脂、SPS琼脂、厌氧巯基培养基是分离和培养的几种培养基。
Himedia Media for Anaerobes  厌氧菌培养基

FD013 S.F.P. Supplement (Perfringens S.F.P. Supplement)
FD045 Egg Yolk Emulsion (50ml / 100 ml per vial)
GM154 Reinforced Clostridial Agar
GM632 SPS Agar
LQ080V Cooked Meat Broth
M1005 S.F.P. Agar Base
M149 Cooked M Medium (R.C.Medium)
M154 Reinforced Clostridial Agar
M1616 Anaerobic Thioglycollate Medium Base
M387 McClung Toabe Agar Base
M632 SPS Agar
M928 Liver Broth
MV1005 S.F.P. HiVeg™ Agar Base
MV154 Reinforced Clostridial HiVeg™ Agar
MV387 McClung Toabe HiVeg™ Agar Base
MV632 SPS HiVeg™ Agar

Himedia兽医用培养基 Veterinary

Himedia兽医用培养基 Veterinary
上海金畔生物科技有限公司,作为HiMedai公司在中国的代理商,在微生物培养和检测领域,会一如既往地为您带来优质的服务。
Himedia代理,欢迎新老客户访问Himedia官网或者咨询我们获取更多有关产品信息。
Veterinary section is concerned with microbial diseases of domesticated animals and wild animals living in captivity and their infections are of interest because of their interrelation with humans (zoonoses) and/or domestic animals. HiMedia provides various media for bacteria, fungi and anaerobes, which are useful in the Veterinary. It also includes Ready Prepared along with Powdered Media for transportation that offers a safe and appropriate way of carrying the samples from distances (long or short). It fastens the growth of microorganisms that helps in perfect isolation. The powdered media are available in both versions i.e. animal and vegetable based peptones.
兽医科涉及被圈养的驯养动物和野生动物的微生物疾病,它们的感染是令人感兴趣的,因为它们与人类(人畜共患病)和(或)家畜有关。HiMedia为细菌、真菌和厌氧菌提供各种培养基,它们在兽医中很有用。它还包括准备与粉末媒体一起运输,提供了一个安全和适当的方式从距离(长或短)的样品。它加快了微生物的生长,有助于完全隔离。粉状介质有两种版本,即以动物和蔬菜为基础的蛋白胨。
Collection & Transport Media
General Purpose Media 通用培养基
Media like Brain Heart Infusion Agar, Nutrient Agar, Tryptose Agar are included in this section for the isolation and cultivation of Bacteria.

Product
EC001CCL HiEncap™ Nutrient Agar
EC001D HiEncap™ Nutrient Agar
EC210CCL HiEncap™ Brain Heart Infusion Broth
EC210D HiEncap™ Brain Heart Infusion Broth
EC211CCL HiEncap™ Brain Heart Infusion Agar (HiEncap™ Special Infusion Agar)
GM001 Nutrient Agar
(Complies as per ISO 17025:2005)
GM009 Fluid Thioglycollate Medium
(Thioglycollate Medium, Fluid)
GM011 Soyabean Casein Digest Medium
(Tryptone Soya Broth)
GM210 Brain Heart Infusion Broth
(Complies as per ISO 17025:2005)
GM211 Brain Heart Infusion Agar
(Special Infusion Agar)
(Complies as per ISO 17025:2005)
GM290 Casein Soyabean Digest Agar
(Soyabean Casein Digest Agar) (Tryptone Soya Agar)
LQ199C Sterile Saline, 0.9%
LQ210C Brain Heart Infusion Broth
LQ210D Brain Heart Infusion Broth
M001 Nutrient Agar
(Complies as per ISO 17025:2005)
M009 Fluid Thioglycollate Medium (Thioglycollate Medium, Fluid)
M011 Soyabean Casein Digest Medium (Tryptone Soya Broth)
M084 Dextrose Agar
M093 Tryptose Phosphate Broth
M158 Azide Blood Agar Base
(Complies as per ISO 17025:2005)
M1902 Nutrient Broth No.3
M210 Brain Heart Infusion Broth
(Complies as per ISO 17025:2005)
M211 Brain Heart Infusion Agar (Special Infusion Agar)
(Complies as per ISO 17025:2005)
M290 Casein Soyabean Digest Agar (Soyabean Casein Digest Agar) (Tryptone Soya Agar)
M428 Eugonic Agar
M538 Tryptose Agar
M834 Blood Agar Base No. 2
(Complies as per ISO 17025:2005)
M883 Meat Infusion Agar (Standard Infusion Agar)
MCD001 Nutrient HiCynth™ Agar
MCD009 Fluid Thioglycollate HiCynth™ Medium (Thioglycollate HiCynth™ Medium, Fluid)
MCD011 Soyabean Casein Digest HiCynth™ Medium (Tryptone Soya HiCynth™ Broth)
MCD210 Brain Heart Infusion HiCynth™ Broth
MCD211 Brain Heart Infusion HiCynth™ Agar (Special Infusion HiCynth™ Agar)
MCD290 Soyabean Casein Digest HiCynth™ Agar (Casein Soyabean Digest HiCynth™ Agar) (Tryptone Soya HiCynth™ Agar)
MCD834 Blood Agar HiCynth™ Base No.2
MP001L Nutrient Agar Plate (150mm plate)
MPV290GT Soyabean HiVeg Agar Plate(Tryptone Soya HiVeg Agar Plate)
MV001 Nutrient HiVeg™ Agar
MV009 Fluid Thioglycollate HiVeg™ Medium
MV011 Soyabean HiVeg™ Medium
MV084 Dextrose HiVeg™ Agar
MV093 Tryptose Phosphate Broth, HiVeg™
MV158 Azide Blood Agar Base, HiVeg™
MV210 Brain Heart Infusion Broth, HiVeg™
MV211 Brain Heart Infusion Agar, HiVeg™
(Special Infusion Agar, HiVeg™)
MV290 Soyabean HiVeg™ Agar
MV428 Eugonic HiVeg™ Agar
MV538 Tryptose Agar, HiVeg™
MV834 Blood Agar Base No. 2, HiVeg™
MV883 Meat Infusion Agar, HiVeg™
(Standard Infusion Agar, HiVeg™)
SM001D Nutrient Agar
SM211D Brain Heart Infusion Agar
SM290D Soyabean Casein Digest Agar

Media for Anaerobes   厌氧菌培养基
Media for Brucella  布鲁氏菌培养基
Media for Enterobacteriaceae  肠杆菌科培养基
Media for Francisella   弗朗西塞拉培养基
Media for Fungi   真菌培养基
Media for Listeria  李斯特菌培养基
Listeriosis is a common condition in some farm outbreaks and to help isolate and cultivate this species. HiMedia has developed a number of media such as Listeria Enrichment Broth, Listeria Identification Agar Base, Listeria Oxford Medium Base etc.
李斯特菌病是一些农场爆发的常见疾病,有助于隔离和培育这一物种。HiMedia公司开发了一系列的培养基,如李斯特菌富集液、李斯特菌鉴定琼脂基地、牛津李斯特菌培养基基地等。

FD061 李斯特菌选择性补充剂(PALCAM) Listeria Selective Supplement (PALCAM)
FD063 李斯特菌选择性补充剂II Listeria Selective Supplement II
FD065 Fraser浓缩补充剂 Fraser Enrichment Supplement
FD071 牛津李斯特菌 Oxford Listeria Supplement
FD125 Fraser选择性补充剂 Fraser Selective Supplement
FD136 UVM补充材料I Listeria UVM Supplement I
FD137 UVM补充材料II Listeria UVM Supplement II
GM1064 李斯特菌鉴定琼脂碱 Listeria Identification Agar Base
(PALCAM) (PALCAM)
(符合ISO 17025:2005) (Complies as per ISO 17025:2005)
GM1083 Fraser二次富集肉汤碱 Fraser Secondary Enrichment Broth Base
(符合ISO 17025:2005) (Complies as per ISO 17025:2005)
GM1145 牛津李斯特菌培养基 Listeria Oxford Medium Base
(符合ISO 17025:2005) (Complies as per ISO 17025:2005)
GM889 李斯特菌选择性肉汤碱 Listeria Selective Broth Base
(符合ISO 17025:2005) (Complies as per ISO 17025:2005)
M1064 李斯特菌鉴定琼脂基(PALCAM) Listeria Identification Agar Base (PALCAM)
(符合ISO 17025:2005) (Complies as per ISO 17025:2005)
M1083 Fraser二次富集肉汤碱 Fraser Secondary Enrichment Broth Base
(符合ISO 17025:2005) (Complies as per ISO 17025:2005)
M1145 牛津李斯特菌培养基 Listeria Oxford Medium Base
(符合ISO 17025:2005) (Complies as per ISO 17025:2005)
M386 麦布莱德李斯特菌琼脂碱 McBride Listeria Agar Base
M567 李斯特菌选择性琼脂(双组分) Listeria Selective Agar (Twin pack)
M569 李斯特菌浓缩肉汤(双组分) Listeria Enrichment Broth (Twin pack)
M889 李斯特菌选择性肉汤碱 Listeria Selective Broth Base
(符合ISO 17025:2005) (Complies as per ISO 17025:2005)
M890A 李斯特菌富集培养基碱(UVM) Listeria Enrichment Medium Base (UVM)
(符合ISO 17025:2005) (Complies as per ISO 17025:2005)
M890M 李斯特菌富集培养基碱 Listeria Enrichment Medium Base, Modifie
MV1064 李斯特菌鉴定™琼脂碱 Listeria Identification HiVeg™ Agar Base
(PALCAM) (PALCAM)
MV1083 Fraser二次富集™肉汤碱 Fraser Secondary Enrichment HiVeg™ Broth Base
MV1145 牛津李斯特菌™培养基 Listeria Oxford HiVeg™ Medium Base
MV386 ™琼脂碱 McBride Listeria HiVeg™ Agar Base
MV567 李斯特菌选择性™琼脂(双组分) Listeria Selective HiVeg™ Agar (Twin pack)
MV569 富李斯特菌™肉汤(双组分) Listeria Enrichment HiVeg™ Broth (Twin pack)
MV889 李斯特菌选择性™肉汤碱 Listeria Selective HiVeg™ Broth Base
MV890A 富李斯特菌™培养基碱 Listeria Enrichment HiVeg™ Medium Base (UVM)

Media for Pseudomonas  假单胞菌培养基
Media for S.agalactiae  赤链霉菌(S.agalactiae)的培养基
Media for Salmonella-Shigella  沙门氏菌媒介-志贺菌
Media for Staphylococci    葡萄球菌培养基
Media for Streptococci  链球菌培养基
Media for Vibrio   弧菌传播培养基

Himedia食品检测用培养基 Food

Himedia食品检测用培养基 Food
上海金畔生物科技有限公司,作为HiMedai公司在中国的代理商,在微生物培养和检测领域,会一如既往地为您带来优质的服务。
Himedia代理,欢迎新老客户访问Himedia官网或者咨询我们获取更多有关产品信息。
Food
Food Microbiology is the detection and analysis of food borne spoilage microorganisms. This field covers, the study of micro-organisms involved in the food; how they can be identified and cultured, how they live, how some of them infect and cause disease and how their activities can be brought in use. It is a very broad section, encompassing the study of microorganisms which have both beneficial and deleterious effects on the quality and safety of raw and processed foods. The primary tool of microbiologists is the ability to identify and quantify the food-borne microorganisms; however the inherent inaccuracies in enumeration processes and the natural variation found in all bacterial populations complicate the microbiologist’s job. HiMedia serve the needs of food processing Industries, by offering a broad range of Culture Medias for the detection of microbes and their activity.
食品微生物学是对食源性腐败微生物的检测和分析。这个领域包括食品中的微生物的研究,如何识别和培养它们,它们是如何生存的,它们中的一些是如何感染和引起疾病的,以及它们的活动是如何发挥作用的。这是一个非常广泛的部分,包括微生物的研究,这些微生物对生食品和加工食品的质量和安全都有利和有害的影响。微生物学家的主要工具是识别和量化食物传播的微生物的能力;然而,计数过程中固有的不准确和在所有细菌种群中发现的自然变异使微生物学家的工作复杂化。HiMedia通过提供广泛的培养媒介来检测微生物及其活动,从而满足食品加工业的需要。
Indicator Microbes & Pathogen  指示微生物和病原体
Microbes in Processing & Spoilage  加工和腐败中的微生物
Preparatory Media  预备培养基

Harlan teklad官网动物饲料代理商 猫 雪貂 反刍动物 国内动物饲料定制

Harlan teklad官网动物饲料代理商 猫 雪貂 反刍动物 国内动物饲料定制

 

特克拉德全球猫粮(2060)是专门用来提供所有已知营养的适当平衡,被认为对研究猫的生长、维持和繁殖是必不可少的。
该饮食提供统一的营养,是一种固定的配方饮食设计,以尽量减少营养差异,否则可能会发生,如果饮食的成分组成从一批改变到下一批。与其他猫粮不同,它不含肉类替代品、人工调味品、过量谷物、化学色素或填充物。
猫有不寻常的营养需求。它们不能有效地将色氨酸转化为烟酸,不能将β胡萝卜素转化为维生素A,也不能去饱和亚油酸。它们需要高水平的蛋白质,而氨基酸牛磺酸是防止眼部损害和扩张性心肌病。特克拉德全球猫粮是为了满足这些特殊需要而设计的。此外,它的配方是低镁和低灰分,高肉类蛋白质,以产生酸性尿液,这降低了猫尿综合征的风险。
喂食方向
特克勒德全球猫饮食是一个完整的饮食为猫和小猫。[医]锂在任何时候都应提供获得饮食的机会。猫通常一天只吃一小部分食物,而且他们有一种正常的倾向,即只吃少量的水。每种动物都应该有淡水。

产品
特克拉德猫粮 不可蒸压式
特克拉德全球猫粮 2060,2060 C
许多饮食都是由符合产品代码的“C”指定的认证格式提供的。当饮食被认证时,一个有代表性的样本会被测试一组污染物。如果没有经过认证的库存,可以根据要求提供认证。可适用最低订货量和附加费用。

雪貂

特克拉德全球雪貂饲料(2072)专为提供对研究雪貂的生长、维持和繁殖所必需的所有已知营养物的适当平衡而制定的。
雪貂实验室饮食提供统一的营养,是一种固定的配方饮食设计,以尽量减少营养变化,否则可能会发生如果饲料的成分组成从一批改变到下一批。
雪貂是一种特殊的食肉动物,肠道很短。人们认为,像猫一样,雪貂不能去饱和亚油酸。由于这些原因,一般建议雪貂日粮中含有大量的动物蛋白质和脂肪。在饮食中添加氨基酸牛磺酸是预防眼部损害和扩张型心肌病的一种安全措施。特克拉德全球雪貂饮食旨在满足这些特殊需要,包括大量的家禽副产品膳食和家禽脂肪。此外,它的配方是低镁和低灰分,这减少了泌尿疾病的风险。不像低质量的雪貂饲料,它不包含肉类替代品,人工调味品,谷物,化学色素,或填料。
喂食方向
特克拉德全球雪貂的饮食是一个完整的饮食Jills,和圣基茨。提供[医]锂在自食其力者中获得饮食的机会。雪貂通常一天只吃一小部分食物,而且他们有一种正常的倾向,即只消耗少量的水。雪貂在任何时候都能很容易地获得新鲜和清洁的食物和水,这一点至关重要。

产品
雪貂饲料 不可蒸压式
特克拉德全球雪貂饲料 2072,2072C
许多饮食都是由符合产品代码的“C”指定的认证格式提供的。当饮食被认证时,一个有代表性的样本会被测试一组污染物。如果没有经过认证的库存,可以根据要求提供认证。可适用最低订货量和附加费用。

反刍动物

反刍动物饮食(7060)是专门为各种实验室反刍动物提供所有已知营养的适当平衡。该饮食提供统一的营养,是一种固定配方的饮食设计,以尽量减少营养差异,否则可能会发生如果饮食成分组成改变从一批到下一批。
反刍动物需要大量纤维以保持瘤胃健康。绵羊需要铜,但对铜的毒性也很敏感。反刍动物日粮中含有丰富的纤维,支持微生物发酵,维持瘤胃功能。该日粮铜含量低,容易超过大多数反刍动物对铜的要求,同时避免了铜对绵羊的毒性。
喂食方向
特克拉德反刍动物的饮食是一个完整的饮食,为各种实验室反刍动物品种,一般应该每天以2%至3%的体重,取决于期望的增长率。淡水应该总是提供给每种动物,特别是在温暖的夏天。

产品
反刍动物饲料 不可蒸压式
反刍动物饮食 7060、7060 C
许多饮食都是由符合产品代码的“C”指定的认证格式提供的。当饮食被认证时,一个有代表性的样本会被测试一组污染物。如果没有经过认证的库存,可以根据要求提供认证。可适用最低订货量和附加费用。

保质期和贮藏期

没有一个确定的点,人们能够预测什么时候一个特定的饮食会变质或变得缺乏一个或多个营养。九个月保质期的共同准则是以北美长期的实践为基础的。在欧洲和亚洲,当地做法和监管监督方面的差异导致特克拉德标准天然成分饮食被例行使用到9个月,有时甚至在生产后12个月。这种实践经验,随着时间的推移,再加上文献支持和维生素测试,让我们相信,这些饮食继续支持动物的健康和研究的完整性,至少在9个月后生产。如果你不确定当地的政策,请向你的机构寻求指导。
建议的储存条件:

  • 凉爽和干燥;在华氏70度或以下,湿度低于50%的理想值,但高达65%是可以接受的。
  • 清洁无害虫
  • 在原始包装中或容器中,防止连续暴露于光线下,并将空气暴露在最小范围内。

Envigo also manufactures and stocks diets for less commonly used laboratory animals including cats, ferrets, and for ruminants such as sheep, goats and cows.

COLLAPSE ALL TABS

Teklad global cat diet (2060) is specifically formulated to provide the proper balance of all known nutrients considered essential for growth, maintenance, and reproduction of research cats.
The diet provides uniform nutrition and is a fixed-formula diet designed to minimize the nutrient variances that otherwise could occur if the ingredient composition of a diet were altered from one batch to the next. Unlike other cat foods, it does not contain meat substitutes, artificial flavorings, excessive grains, chemical colorings, or fillers.
Cats have unusual nutritional requirements. They cannot convert tryptophan to niacin effectively, cannot convert beta carotene to vitamin A, and cannot desaturate linoleic acid. They require an elevated level of protein, and the amino acid taurine is needed to prevent ocular lesions and dilated cardiomyopathy. Teklad global cat diet is designed to meet these special needs. In addition, it is formulated to be low in magnesium and ash, and high in meat protein to produce an acidic urine, which reduces the risk of feline urinary syndrome.
Feeding directions
Teklad global cat diet is a complete diet for cats and kittens. Ad libitum access to diet should be provided at all times. Cats normally consume small portions of food throughout the day, and they have a normal propensity to consume minimal amounts of water. Fresh water always should be available to each animal.

Products
Teklad cat diets Non-autoclavable form
Teklad global cat diet 2060, 2060C
Many diets are available in certified format designated by a “C” following the product code. When diets are certified a representative sample is tested for a panel of contaminants. If not stocked as certified, certification can be made available upon request. Minimum order size and additional charges may apply.
Teklad global ferret diet (2072) is specifically formulated to provide the proper balance of all known nutrients considered essential for growth, maintenance, and reproduction of research ferrets.
The ferret laboratory diet provides uniform nutrition and is a Fixed Formula diet designed to minimize the nutrient variances that otherwise could occur if the ingredient composition of a diet were altered from one batch to the next.
Ferrets are obligate carnivores with a very short intestinal tract. It is assumed that like cats, ferrets cannot desaturate linoleic acid. For these reasons it is generally recommended that ferret diets contain high amounts of animal protein and fat. The amino acid taurine is supplemented in the diet as a safety measure against developing ocular lesions and dilated cardiomyopathy. Teklad global ferret diet is designed to meet these special needs by including a large amount of poultry by-product meal and poultry fat. In addition, it is formulated to be low in magnesium and ash, which reduces the risk of urinary disease. Unlike lower quality ferret diets, it does not contain meat substitutes, artificial flavorings, grains, chemical colorings, or fillers.
Feeding directions
Teklad global ferret diet is a complete diet for jills, and kitts. Provide ad libitum access to diet in a self-feeder. Ferrets normally consume small portions of food throughout the day, and they have a normal propensity to consume minimal amounts of water. It is crucial that fresh and clean food and water be kept easily accessible to ferrets at all times.

Products
Teklad ferret diets Non-autoclavable form
Teklad global ferret diet 2072, 2072C
Many diets are available in certified format designated by a “C” following the product code. When diets are certified a representative sample is tested for a panel of contaminants. If not stocked as certified, certification can be made available upon request. Minimum order size and additional charges may apply.
Teklad ruminant diet (7060) is specifically formulated to provide the proper balance of all known nutrients to a variety of laboratory ruminant species. The diet provides uniform nutrition and is a fixed-formula diet designed to minimize the nutrient variances which otherwise could occur if the ingredient composition of a diet were altered from one batch to the next.
Ruminants require significant fiber to maintain proper rumen health. Sheep have a requirement for copper but are also very susceptible to copper toxicity. Teklad ruminant diet is high in fiber to support microbial fermentation and maintain proper rumen function. The diet has a low copper content easily exceeding the copper requirements of most ruminants while avoiding copper toxicity in sheep.
Feeding directions
Teklad ruminant diet is a complete diet for a variety of laboratory ruminant species and should generally be fed daily at two-to-three percent of body weight depending on the desired rate of gain. Fresh water always should be available to each animal particularly during warm summer days.

Products
Teklad ruminant diets Non-autoclavable Form
Teklad ruminant diet 7060, 7060C
Many diets are available in certified format designated by a “C” following the product code. When diets are certified a representative sample is tested for a panel of contaminants. If not stocked as certified, certification can be made available upon request. Minimum order size and additional charges may apply.
There is no definitive point where one is able to predict when a specific diet will spoil or become deficient in one or more nutrients. The common guideline of a nine month shelf life is based on longstanding practice in North America. In Europe and Asia, differences in local practices and regulatory oversight have led to Teklad standard natural ingredient diets being routinely used out to nine months and sometimes 12 months post-manufacture. This practical experience, along with literature support and vitamin testing over time, gives us confidence that these diets continue to support animal health and study integrity out to at least nine months post-manufacture. Please refer to your institution for guidance if you are unsure of local policies.
Recommended storage conditions:

  • Cool and dry; at or below 70 degrees fahrenheit, humidity below 50% ideal, but up to 65% is acceptable
  • Clean and free of pests
  • In original packaging or in a container that prevents continuous exposure to light and minimal exposure to air

Harlan teklad官网动物饲料 Guinea pig diets 豚鼠饮食 上海动物饲料定制

Harlan teklad官网动物饲料 Guinea pig diets 豚鼠饮食 上海动物饲料定制
特克勒德豚鼠饮食是为了满足豚鼠在生命周期的各个阶段的营养需要而制定的完整和平衡的饮食。
植物和鱼粉来源所提供的蛋白质提供了豚鼠所需必需氨基酸的平衡。大豆油中的脂肪提供了良好的毛发所必需的脂肪酸。
特克拉德豚鼠的饮食适当强化维生素和矿物质,以满足豚鼠在生长、维持和繁殖过程中的需要。
维生素C被包括在这些饮食中,因为豚鼠(就像人类和其他灵长类动物一样)需要饮食中的维生素C来防止坏血病。稳定维生素C(L-抗坏血酸-2-聚磷酸)用于延长保质期.
紫花苜蓿粉是一种高品质的饲料产品,有助于维持豚鼠消化系统的正常运转。该公司,颗粒饮食有助于防止饲料浪费。
产品
特克乐豚鼠饲料 不可蒸压式 辐照
全球豚鼠饮食 2040,2040 C 2940
全球高纤维豚鼠饮食 2041 2941
特克乐豚鼠饲料 7006
并不是所有的产品都是在当地库存的,可能需要延长交货期和额外的费用。
许多饮食都是由符合产品代码的“C”指定的认证格式提供的。当饮食被认证时,一个有代表性的样本会被测试一组污染物。如果没有经过认证的库存,可以根据要求提供认证。可适用最低订货量和附加费用。
折叠所有标签

没有一个确定的点,人们能够预测什么时候一个特定的饮食会变质或变得缺乏一个或多个营养。六个月保质期的共同准则是以北美长期的实践为基础的。在欧洲和亚洲,当地做法和监管监督方面的差异导致特克拉德标准天然成分饮食被例行使用到9个月,有时甚至在生产后12个月。这种实践经验,随着时间的推移,再加上文献支持和维生素测试,让我们相信,这些饮食继续支持动物的健康和研究的完整性,至少在9个月后生产。如果你不确定当地的政策,请向你的机构寻求指导。
建议的储存条件:

  • 凉爽和干燥;在华氏70度或以下,湿度低于50%的理想值,但高达65%是可以接受的。
  • 清洁无害虫
  • 在原始包装中或容器中,防止连续暴露于光线下,并将空气暴露在最小范围内。
应该允许几内亚猪[医]锂获得放置在笼的前部或侧面的喂食器中的食物。

Teklad guinea pig diets are complete and balanced diets formulated to meet the nutritional needs of guinea pigs during various stages of the life cycle.
Protein supplied by plant and fish meal sources provides the balance of essential amino acids required by guinea pigs. Fat from soybean oil supplies essential fatty acids necessary for a good hair coat.
Teklad guinea pig diets are properly fortified with vitamins and minerals to meet the needs of guinea pigs during growth, maintenance, and reproduction.
Vitamin C is included in these diets because guinea pigs (as do man and other primates) require a dietary source of vitamin C to prevent scurvy. Stabilized vitamin C (L-ascorbyl-2-polyphosphate) is used to extend the shelf life.
Alfalfa meal is included as a high-quality forage product to help maintain the normal functioning of the guinea pig’s digestive system. The firm, pelleted diet aids in preventing feed wastage.

Products
Teklad guinea pig diets Non-autoclavable form Irradiated
Teklad global guinea pig diet 2040, 2040C 2940
Teklad global high fiber guinea pig diet 2041 2941
Teklad guinea pig diet 7006
Not all products are stocked locally; extended lead time and additional fees may apply.
Many diets are available in certified format designated by a “C” following the product code. When diets are certified a representative sample is tested for a panel of contaminants. If not stocked as certified, certification can be made available upon request. Minimum order size and additional charges may apply.
COLLAPSE ALL TABS

There is no definitive point where one is able to predict when a specific diet will spoil or become deficient in one or more nutrients. The common guideline of a six month shelf life is based on longstanding practice in North America. In Europe and Asia, differences in local practices and regulatory oversight have led to Teklad standard natural ingredient diets being routinely used out to nine months and sometimes 12 months post-manufacture. This practical experience, along with literature support and vitamin testing over time, gives us confidence that these diets continue to support animal health and study integrity out to at least nine months post-manufacture. Please refer to your institution for guidance if you are unsure of local policies.
Recommended storage conditions:

  • Cool and dry; at or below 70 degrees fahrenheit, humidity below 50% ideal, but up to 65% is acceptable
  • Clean and free of pests
  • In original packaging or in a container that prevents continuous exposure to light and minimal exposure to air
Guinea pigs should be allowed ad libitum access to diets placed in a feeder attached to the front or side of the cage.

harlan Teklad diet, bedding and enrichment 饮食、垫料和营养丰富动物饲料

harlan Teklad diet, bedding and enrichment 饮食、垫料和营养丰富动物饲料

饮食、垫料和营养丰富

你的研究成果在很大程度上取决于你的研究模型是什么。确保你的研究动物有最适当的饮食是保持一致,可靠的研究数据的关键。你是否需要一个标准啮齿动物饮食或者是定制研究饮食,我们知道如何提供健全的营养解决方案。
依靠我们对你的研究和动物福利的承诺来保护你工作的潜力。了解Envigo实验室动物饮食如何帮助您提高您的研究:
通过提供全方位的实验动物饮食,床上用品和丰富,Envigo作为您的研究需求的一站式供应商。
折叠所有标签

各种实验室动物的标准天然成分饮食由谷物、植物和动物蛋白质等农产品组成。这些食物被用来满足动物群体在繁殖、生长和维持方面的日常需要。如果仔细选择,它们也可以支持许多研究目标。
所有特克拉德标准天然配料饮食的特点是我们的固定配方理念,加上严格的配料采购实践,然后是自动化和受控的生产实践。常规的,可蒸压的,认证的,和辐照实验日粮是众多选择之一。
了解更多关于标准天然成分饮食的知识
如果你需要控制营养,诱发疾病或提供特定剂量的饮食,你可以利用我们的经验,净化或其他类型的定制研究饮食。我们的营养学家可以与您独特的规格,以找到一个符合您的研究要求的特克乐解决方案。
了解更多关于定制研究饮食的信息
为了治疗一种疾病或预防疾病或暴发,使用由兽医指导的特克勒德药物饮食可以支持储存的药物饮食。定制饮食与各种药物或化合物也可以添加在我们的定制研究饮食设施的要求。

What comes out of your research depends in large part on what goes into your research models. Ensuring your study animals have the most appropriate diet is critical to maintaining consistent, reliable research data. Whether you need a standard rodent diet or a custom research diet, we know how to provide sound nutrition solutions.
Protect the potential of your work by relying on our commitment to your research and animal welfare. Learn how Envigo laboratory animal diets can help advance your studies with:

By providing a full range of lab animal diets, bedding and enrichment, Envigo serves as your one-stop supplier for your research needs.

COLLAPSE ALL TABS

Standard natural ingredient diets for a variety of laboratory animal species are comprised of agricultural commodities such as grains, and plant and animal proteins. These diets are used to meet the everyday needs of animal colonies for breeding, growth and maintenance. When carefully chosen, they also can support many research objectives.
The hallmark of all Teklad standard natural ingredient diets is our fixed formulation philosophy coupled with stringent ingredient procurement practices, followed by automated and controlled manufacturing practices. Regular, autoclavable, certified, and irradiated laboratory diets are among the many options.
Learn more about standard natural ingredient diets
If you need to control nutrients, induce disease or provide specific doses through a diet, you can leverage our experience with purified or other types of custom research diets. Our nutritionists can work with your unique specifications to find a Teklad solution that meets your study’s requirements.
Learn more about custom research diets
For treatment of a condition or to prevent illness or outbreak, the use of Teklad medicated diets as directed by a veterinarian can be supported by stocked medicated diets. Custom diets with various medications or compounds can also be added by request at our custom research diet facility.
Learn more about medicated diets

harlan teklad官网动物饲料 兔子 猪 几内亚猪 仓鼠、沙土鼠 TD.92033猪日粮

The most common custom rabbit diets are those with a standard diet base and added cholesterol. Typically, the added cholesterol ranges from 0.25% to two percent. Additional fat can also be a feature of these formulas. To preserve pellet quality we recommend no more than six percent additional fat. Added fat is most often supplied as peanut oil, corn oil, coconut oil, or a combination. We recommend the Teklad base diets 2030 or 2031.
Rabbits do not readily consume purified diet. When specific nutrient manipulations are necessary, hybrid diets or at least some alfalfa meal inclusion is recommended. Contact us for formula examples or to discuss your specific needs.
Most often, customized diets for swine feature natural ingredients with added fat and cholesterol. Here are three variations on this theme:

  • TD.92033      Swine diet (15% lard, 1.2% cholesterol)
  • TD.92052      Swine diet (15% lard, 1.5% cholesterol)
  • TD.93296      Swine diet (15% lard, two perecent cholesterol)

We recommend these diets in meal/powder form, as pellets are not very durable. Other natural ingredient and purified diets with various nutrient manipulations are available. Contact us for further information.

The most common custom Guinea pig diets are those with a standard diet base (such as Teklad 2040 or 2041) and added cholesterol.
Guinea pigs do not readily consume purified diets, so when specific nutrient manipulations are necessary, hybrid diets (mixture of refined and natural ingredients) are recommended. At the very least it is advisable to retain some alfalfa meal in the diet. Contact us for further information.
Most times, diets that are developed for mice and rats are suitable for hamsters and gerbils, and vice versa. We may advise increasing specific nutrients in a purified diet for hamsters and gerbils. Contact us for further information.
Depending on the focus of your research, customized diet for non-human primates can contain natural ingredients, refined ingredients, or a mixture of both.  Custom diets for primates often feature adjustments in fat type, fat level, and cholesterol. Contact us for further information.

Harlan teklad官网动物饲料 异黄酮调节 AIN-76A AIN-93g AIN-93M

异黄酮调节 Isoflavone adjusted

Harlan teklad官网动物饲料 异黄酮调节 AIN-76A,AIN-93g,AIN-93M

异黄酮是一种植物雌激素,存在于大豆蛋白中。大多数传统的标准饮食以豆粕为主要成分,因此是异黄酮的重要来源。请参阅常见问题有关植物雌激素的更多信息。
相比之下,酪蛋白基础的纯化饮食,如AIN-76A,AIN-93g,AIN-93M,以及含有类似成分的配方,基本上不含异黄酮。这种类型的饮食有时被用于研究,需要最低限度的异黄酮背景。这种饮食可以作为异黄酮如染料木黄酮(Genistein)的背景。客户提供的)可以添加。
一种替代纯酪蛋白饮食的方法是我们的全球啮齿动物饮食系列中的天然成分饮食。这一系列中的几种饮食含有极小的异黄酮/植物雌激素水平,并且通常用于需要最小异黄酮/植物雌激素背景的研究。这类饮食也可用作异黄酮如染料木素(Genistein)的背景。客户提供的)可以添加。

Isoflavones, a type of phytoestrogen, are found in soy protein. Most traditional standard diets have soybean meal as a major ingredient, and therefore are a significant source of isoflavones. Please refer to FAQ section for more information about phytoestrogens.
In contrast, casein-based purified diets such as AIN-76A, AIN-93G, AIN-93M, and formulas with similar ingredients, are essentially free of isoflavones. This type of diet is sometimes used for research that requires a minimal isoflavone background. This type of diet can be used as the background to which isoflavones such as genistein (supplied by the customer) can be added.
An alternative to a purified, casein-based diet is a natural ingredient diet from our global rodent diet line. Several diets in this line contain minimal isoflavone/phytoestrogen levels and are commonly used for research that requires a minimal isoflavone/phytoestrogen background. This type of diet can also be used as the background to which isoflavones such as genistein (supplied by the customer) can be added.

harlan teklad官网动物饲料代理商 他莫昔芬饮食 Tamoxifen diets TD.130855

harlan teklad官网动物饲料代理商

他莫昔芬饮食 harlan teklad官网动物饲料代理商 他莫昔芬饮食 Tamoxifen diets TD.130855

他莫昔芬激活Creer的饮食

有几篇文献引用了含有他莫昔芬的饮食对CRE模型在雌激素受体突变的控制下的应用。恩维戈特克乐饮食使各种含他莫昔芬的饮食定制,以满足您的研究需要。我们还制作了各种各样的含多西环素饮食对于被监管的系统。如果你有任何问题,请咨询营养师。

枸橼酸他莫昔芬和他莫昔芬

他莫昔芬作为他莫昔芬-蔗糖混合物添加到饮食中.鼓励用户使用库存供应。然而,泰克乐将继续与客户准备的混合。如果您选择此选项,请咨询营养师,以获得有关配制和发送混合物的更多信息。
鼓励用户从以下库存选项中进行选择,以便在几天内随时可供装运。
特克乐提供USP级三苯氧胺和枸橼酸他莫昔芬的饮食。
他莫昔芬
每公斤饲料毫克
日他莫昔芬
每公斤体重毫克1
饮食编码
(特克勒德供应他莫昔芬)
    天然色 红色
250 40 TD.130855 TD.130856
500 80 TD.130857 TD.130858
400柠檬酸盐2 40 TD.130859 TD.1308603
1假设体重20-25克,摄入量3-4克。
2枸橼酸他莫昔芬为66%他莫昔芬
3在欧洲称为TAM 400/Creer(TD.55125)
请为辐照饮食增加5-10天的准备时间;库存和定制产品至少需要3公斤订单。
这些饲料都有他莫昔芬与~5%蔗糖预混合,作为一种适口性增强剂;然而,饲料厌恶仍有可能发生。如果摄入是一个问题,请参阅下面的建议。
TeculadGlobal2016-这些例子中的基础饮食-仅仅是少数几种植物雌激素饮食中的一种。咨询营养学家关于其他基础饮食的使用。
折叠所有标签

  • 最低订货量为3公斤,足以喂养20只小鼠一个月。
  • 储存冷冻饮食,并计划在六个月内使用。
  • 典型的准备时间为两周(如果经过辐照,则为四周)
  • 辐照(可选)20 kGy的最低剂量(必须按顺序要求)
  • 订购:请致电800.483.5523或在线启动订单
计划:

  • 最初减少食物摄入量和减肥
  • 日常观察动物的耐受性-咨询您的IACUC监测指标。
  • 必要时进行干预
如果摄入似乎是一个问题:

  • 通过进行他莫昔芬给药试验,确定低剂量对你的模型是否有效。
  • 用含他莫昔芬颗粒与常规饲料颗粒混合逐渐驯服小鼠
  • 把食物弄湿,然后放在笼子里的盘子里(需要每天更换)。
  • 平日喂饲他莫昔芬饮食,周末有规律饮食。
  • 每隔一周(三苯氧胺饮食两周,休息一周)进行更长时间的治疗
  • 他莫昔芬是一种选择性雌激素受体调节剂(SERM),这意味着它可以抑制雌激素的作用或具有促进雌激素的作用。
  • 人体治疗效果的一般剂量为20毫克/天。用于啮齿动物的他莫昔芬饮食通常含有~1至2毫克/粒。
  • 当处理饮食时,可以使用典型的实验室预防措施,如实验室外套、手套和面罩,尽量减少接触他莫昔芬的事故。
  • 您的化学品安全部门应联系,以获得更多的机构特定的指导方针,以处理和处置含有他莫昔芬的饮食。
  • 治疗时间从一周到两周不等。1,2,5,6,7,8一至两个月3,4,8
  • 纯他莫昔芬1,5,8和枸橼酸他莫昔芬1,2,3,4,6,7都是有效的
  • 通常他莫昔芬剂量为每天40-80毫克/公斤体重。
  • 纯他莫昔芬的典型包合物为250 mg。8或500毫克1,5枸橼酸他莫昔芬为每公斤400毫克。1,2,3,4,6,7
  • 报告的初始重量损失为10%。1,2,4,7,8,与食物摄入量减少有关2
  • 恢复正常饮食后体重的恢复可能会因基因失活而受损。2,7
  1. 安德森·KB,Winer LH,Mork HK,Molkentin JD,Jaisser F.2010。他莫昔芬诱导CRE介导的小鼠心脏基因断裂的给药途径和剂量。 转基因RES 19:715-725。
  2. 蒋介明,凌杰,郑永赫,价格DL,Aja SM,Wong PC.2010年。TDP-43的缺失下调了与肥胖相关的基因Tbc1d1,并改变了身体的脂肪代谢。 美国Acad Sci美国:16320-16324。
  3. Kardakaris R.,Gareus R.,Xandomlea S,Pasparakis M.2011。内皮和巨噬细胞特异性P38αMAPK缺乏不影响ApoE-/-小鼠动脉粥样硬化的发病机制。 PLOSOne 6:e21055。
  4. [2]Kiermayer C,Conrad M,Schneider M,Schmidt J,Brielmeier M.枸橼酸他莫昔芬口服对小鼠心脏时空基因灭活的优化。 创世纪45:11-16。
  5. Koitabashi N,Bedja D,Zaiman AL,Pinto Ym,Zhang M,Gabrielson KL,Takimoto E,Kass DA。2009年。心肌细胞靶向他莫昔芬诱导MerCreMer基因缺失模型中短暂性心肌病的避免。 中国保监会第105:12-15号决议
  6. Kratsios P,Catela C,Salimova E,Huth M,Berno V,Rosenthal N,Morkioti F.2009。细胞自主Notch信号在胚胎和成年心脏心肌细胞中的独特作用。 PCirc第106:559-572号决议。
  7. Miro-Murillo M,Elorza A,Soro-ArNaiz I,Albacete-Albacete L,Ordonz A,Balsa E,Vara-Vega A,Vazquez S,Fuertes E,Fernandez-Criado C,Landazuri MO,Aragones J.2011。急性VHL基因失活可诱导心脏HIF依赖的促红细胞生成素基因表达. PLOS One 6:E 22589。
  8. Welle S,Burgess K,Thornton CA,Tawil R.2009。成熟小鼠肌生长抑素耗竭程度与肌肉生长的关系。 李玉玲.医学杂志.1997(4):E 935-40.

Tamoxifen diets

Diets with tamoxifen activate CreER

Several references cite use of tamoxifen-containing diets for models with Cre under the control of a mutated estrogen receptor. Envigo Teklad diets makes a variety of tamoxifen-containing diets customized to meet your research needs. We also make a variety of doxycycline-containing diets for tet regulated systems. If you have any questions, don’t hesitate to consult a nutritionist.

Teklad stocks tamoxifen and tamoxifen citrate

Tamoxifen is added to the diet as a tamoxifen-sucrose mixture. Users are encouraged to use the stocked supply. However, Teklad will continue to work with customer prepared mixes. If you choose this option, please consult a nutritionist for additional information about preparing and sending the mixture.
Users are encouraged to select from the stocked options below supply readily available to ship within days.
Teklad offers diet with USP grade tamoxifen and tamoxifen citrate
Tamoxifen
mg per kg diet
Daily tamoxifen
mg per kg body weight1
Diet code
(Teklad supplied tamoxifen)
    Natural colored Red
250 40 TD.130855 TD.130856
500 80 TD.130857 TD.130858
400 citrate2 40 TD.130859 TD.1308603
1 Assumes 20-25 g body weight and three-four g intake
2 Tamoxifen citrate is 66% tamoxifen
3 Referred to as TAM400/CreER in Europe (TD.55125)

Please add 5-10 day lead time for irradiated diets; minimum 3 kg orders are required for stocked and customized items.
These diets all have tamoxifen premixed with ~five percent sucrose as a palatability enhancer; however, feed aversion may still occur. If intake is a problem, see below for advice.
Teklad Global 2016 — base diet in these examples — is only one of several minimal phytoestrogen diets Teklad produces. Consult a nutritionist about use of other base diets.
COLLAPSE ALL TABS

  • Minimum order quantity is three kg, sufficient for feeding ~20 mice for one month
  • Store diet refrigerated and plan to use within six months
  • Typical lead time is two weeks (four weeks if irradiated)
  • Irradiation (optional) minimal dose of 20 kGy (Must be requested at time of order)
  • To place an order: contact Teklad Customer Service at 800.483.5523 or initiate order online
Plan for:

  • Initial reduction in food intake and weight loss
  • Daily observation of animal tolerance — consult your IACUC for monitoring metrics
  • Intervene when necessary
If intake seems to be a problem:

  • Determine if a lower dose is effective for your model by conducting a tamoxifen dose feeding trial
  • Gradually acclimate mice by mixing tamoxifen-containing pellets with regular feed pellets
  • Wet the food, then place in a dish inside the cage (requires daily replacement)
  • Feed tamoxifen diet on weekdays, regular diet on weekends
  • Alternate weeks (two weeks on tamoxifen diet, one week off) for longer treatments
  • Tamoxifen is a selective estrogen receptor modulator (SERM) meaning it can repress actions of estrogen or have pro-estrogen effects
  • Usual dose for therapeutic effects in humans is 20 mg/day. Tamoxifen diets for rodents typically contain ~one to two mg/pellet
  • Accidental tamoxifen exposure can be minimized by using typical lab precautions of lab coat, gloves, and mask when handling the diet.
  • Your chemical safety department should be contacted for additional institution specific guidelines for handling and disposal of tamoxifen containing diets.
  • Length of treatment varies from one to two weeks1,2,5,6,7,8 to one to two months3,4,8
  • Pure tamoxifen1,5,8 and tamoxifen citrate1,2,3,4,6,7 are both effective
  • Usual tamoxifen doses are ~40-80 mg per kg body weight per day
  • Typical inclusion for pure tamoxifen is 250 mg8 or 500 mg1,5 and for tamoxifen citrate is 400 mg per kg diet1,2,3,4,6,7
  • Initial weight loss of ten % is reported1,2,4,7,8, associated with reduced food intake2
  • Subsequent recovery of body weight after returning to regular diet may be compromised by gene inactivation2,7
  1. Andersson KB, Winer LH, Mork HK, Molkentin JD, Jaisser F. 2010. Tamoxifen administration routes and dosage for inducible Cre-mediated gene disruption in mouse hearts. Transgenic Res 19:715-725.
  2. Chiang PM, Ling J, Jeong YH, Price DL, Aja SM, Wong PC. 2010. Deletion of TDP-43 down-regulates Tbc1d1, a gene linked to obesity, and alters body fat metabolism. Proc Natl Acad Sci USA 107:16320-16324.
  3. Kardakaris R, Gareus R, Xanthoulea S, Pasparakis M. 2011. Endothelial and macrophage-specific deficiency of P38alpha MAPK does not affect the pathogenesis of atherosclerosis in ApoE-/- mice. PLoS One 6:e21055.
  4. Kiermayer C, Conrad M, Schneider M, Schmidt J, Brielmeier M. 2007. Optimization of spatiotemporal gene inactivation in mouse heart by oral application of tamoxifen citrate. Genesis 45:11-16.
  5. Koitabashi N, Bedja D, Zaiman AL, Pinto YM, Zhang M, Gabrielson KL, Takimoto E, Kass DA. 2009. Avoidance of transient cardiomyopathy in cardiomyocyte-targeted tamoxifen-induced MerCreMer gene deletion models. Circ Res 105:12-15.
  6. Kratsios P, Catela C, Salimova E, Huth M, Berno V, Rosenthal N, Mourkioti F. 2009. Distinct roles for cell-autonomous Notch signaling in cardiomyocytes of the embryonic and adult heart. PCirc Res 106:559-572.
  7. Miro-Murillo M, Elorza A, Soro-Arnaiz I, Albacete-Albacete L, Ordonez A, Balsa E, Vara-Vega A, Vazquez S, Fuertes E, Fernandez-Criado C, Landazuri MO, Aragones J. 2011. Acute Vhl gene inactivation induces cardiac HIF-dependent erythropoietin gene expression. PLoS One 6:e22589.
  8. Welle S, Burgess K, Thornton CA, Tawil R. 2009. Relation between extent of myostatin depletion and muscle growth in mature mice. Am J Physiol Endocrinol Metab.Oct;297(4):E935-40.

harlan teklad官网动物饲料代理商 强力霉素 多西环素 TD.01306 TD.05125 Doxycycline diets

harlan teklad官网动物饲料代理商 强力霉素 多西环素 TD.01306 TD.05125

多西环素饮食

EnvigoTeclad饮食使各种多西环素包含饮食为您的Tet调节系统。可以添加一系列的多西环素(如强力霉素)。典型的包含率是200毫克/千克和625毫克/千克,但一些研究人员指定一个更高或更低的水平。
饮食是很容易定制的,因为他们是新鲜的,当订购。我们目前有超过150个不同的强力霉素配方组合。我们可能有一个现有的产品编号,以满足您的规格。规格包括:基础饮食,多西环素浓度和食用色素。联系我们如果你在下面找不到合适的选择的话,来讨论你的需求。
全球饮食基础
产品编号 基础饮食 强力霉素透明
每公斤饲料毫克
每日强力霉素
3-5克日粮中的毫克
替代
食用色素
TD.01306
备好
2018 625 1.6 – 2.7 TD.08541红色
TD.120769蓝色
TD.00502 2018 200 0.5 – 0.9 TD.04104绿色
TD.110720 2020 625 1.6 – 2.7 TD.130141红色
TD.09651 2019 625 1.6 – 2.7 TD.09761绿色
TD.02503 2016 625 1.6 – 2.7 TD.140263蓝色
TD.00426 2014 625 1.6 – 2.7 TD.07382红色
传统饮食基础
产品编号 基础饮食 强力霉素透明
每公斤饲料毫克
每日强力霉素
3-5克日粮中的毫克
替代
食用色素
TD.05125 7012 625 1.6 – 2.7 TD.08434蓝色
TD.98186 7012 200 0.5 – 0.9 红色
与给水相比,饮食分娩是许多研究人员的一个更好的选择。

  • 饮食能保护身体免受光线伤害。水可能必须用深色或铝箔包装的瓶子浇水。
  • 饮食通常每周改变一次。水可能需要每隔几天更换一次。
  • 饮食供应也可以减少脱水的风险,并避免需要给予蔗糖(考索恩等)。艾尔。(2007年)

含有多西环素的饮食经常以辐照形式订购。辐照必须在订购时要求,并将增加大约两周的准备时间。
如果你的工作需要不含苜蓿的食物进行荧光成像,可以考虑使用全球啮齿动物的饮食基础。如果需要进一步的成像清晰度,我们可以用多西环素进行纯化饮食。
联系我们根据您的具体需求,我们可以推荐一个现有的产品代码或创建一个新的配方。

Doxycycline diets | Envigo

Envigo Teklad diets makes a variety of doxycycline containing diets for your Tet regulated systems. A range of levels of doxycycline (as doxycycline hyclate) can be added. Typical inclusion rates are 200 and 625 mg/kg diet, but some researchers specify a higher or lower level.
Diets are easily customizable as they are made fresh when ordered. We currently have over 150 different doxycycline formula combinations. We likely have an existing product number to meet your specifications. Specifications include: base diet, concentration of doxycycline, and food coloring.
Global diet base
Product number Base diet Doxycycline hyclate
mg per kg diet
Daily doxycycline
mg in 3-5 g diet
Alternative
with food coloring
TD.01306
stocked
2018 625 1.6 – 2.7 TD.08541Red
TD.120769Blue
TD.00502 2018 200 0.5 – 0.9 TD.04104Green
TD.110720 2020 625 1.6 – 2.7 TD.130141Red
TD.09651 2019 625 1.6 – 2.7 TD.09761Green
TD.02503 2016 625 1.6 – 2.7 TD.140263Blue
TD.00426 2014 625 1.6 – 2.7 TD.07382Red
Traditional diet base
Product number Base diet Doxycycline hyclate
mg per kg diet
Daily doxycycline
mg in 3-5 g diet
Alternative
with food coloring
TD.05125 7012 625 1.6 – 2.7 TD.08434Blue
TD.98186 7012 200 0.5 – 0.9 Red
Compared to water delivery, diet delivery is a preferable option for many researchers.

  • Diet offers protection from light. Water may have to be given in dark-colored or foil-wrapped bottles
  • Diet is typically changed once per week. Water may need to be changed every few days
  • Diet delivery may also reduce risk of dehydration and preclude the need to give with sucrose (Cawthorne et. al. 2007)

Doxycycline containing diets are often ordered in irradiated form. Irradiation must be requested at the time of ordering and will add approximately two weeks to the lead time.
If your work requires an alfalfa-free diet for fluorescent imaging, consider using a global rodent diet base. If further imaging clarity is needed, we can make purified diets with doxycycline.
 

harlan teklad官网 动物饲料 矿物调整饮食 TD.80396缺铁饮食 TD.85419缺锌饮食


harlan teklad官网 动物饲料 矿物调整饮食 TD.80396缺铁饮食 TD.85419缺锌饮食

矿物调整饮食

一些矿物调整公式如下所示。请与我们联系,以获得更多的这种性质的配方,或更多的信息,改变矿物质的饮食。有关更多信息,请阅读下面。
公式示例:

独特的蛋白质成分可能是必要的,以尽量减少某些矿物质的背景水平。为尽量减少背景矿物污染而采取的其他步骤包括在必要时使用试剂级矿物或遗漏某些成分。在这些饮食中可以使用特殊的矿物预混料,也可以在饮食中单独添加矿物质,以控制特定矿物质的含量。
除钠外,必须使用精制成分,以达到饮食中矿物质含量尽可能低的水平。
从这种矿物缺乏的基础,不同水平的矿物可以补充回来。一些配方调整多种矿物质和其他相关营养素。
联系我们讨论上述矿物和未列出的矿物的其他可能性。

Mineral adjusted diets | Envigo

A few mineral adjusted formulas are shown below. Please contact us for additional formulas of this nature or for more information about altering the mineral profile of a diet. Read below for more information.
Formula examples:

  • TD.80396      Iron deficient diet
  • TD.85419      Zinc deficient diet
  • TD.88239      Potassium deficient diet
  • TD.95027      Low calcium diet (0.4% P)
  • TD.96348      Diet (20% lactose, 2% Ca, 1.25% P)
  • TD.92163      Selenium deficient diet
  • TD.95125      Iodine deficient (0.15% PTU)

Unique protein ingredients may be necessary to minimize background levels of certain minerals. Other steps taken to minimize background mineral contamination include the use of reagent grade minerals when necessary or omission of certain ingredients. Specialized mineral premixes may be used in these diets, or minerals are added individually to the diet in order to control the level of specific minerals.
With the exception of sodium, it is necessary to use refined ingredients to achieve the lowest possible levels of minerals in a diet.
From this mineral deficient base, various levels of minerals can be added back. Some formulas adjust multiple minerals, and other related nutrients.
Contact us to discuss other possibilities for the minerals listed above, and for those minerals not listed here.

harlan teklad官网TD.02028 TD.02028 TD.96121 动物饲料 胆固醇和胆酸盐来源的纯化高脂饮食


harlan teklad官网TD.02028 TD.02028 TD.96121 动物饲料 胆固醇和胆酸盐来源的纯化高脂饮食
野生型小鼠和大鼠一般对动脉粥样硬化有抵抗力,需要更极端的饮食操作来改变脂蛋白谱,形成轻度动脉粥样硬化(泡沫细胞、脂肪条纹)。现代配方完全是由纯化成分制成的,因为据报道,这种更精细的方法可以减少较少精制和较传统饮食方法引起的胆结石和肝脏损害的发生率。为了在野生型动物中诱导轻度动脉粥样硬化,可对“西方”纯化饲料进行改良,以提高胆固醇(1-1.25%),并添加胆酸钠或胆酸等胆盐。联系我们获得更多的信息,修改,或可能的控制饮食。
添加胆固醇和胆酸盐来源的纯化高脂饮食的例子*:

  • TD.0202821%乳脂(1.25%胆固醇,0.5%胆酸)
  • TD.0923715%乳脂饮食(1%胆固醇,0.5%胆酸钠)

添加胆固醇的纯化高脂饮食的例子(没有胆酸来源):

研究用途:
主要在野生型小鼠和大鼠诱发高胆固醇血症和轻度动脉粥样硬化(泡沫细胞、脂肪条纹)。
不会助长肥胖。
主要饮食特征:

  • 高脂饮食(体重15-20%;脂肪34-45千卡)
  • 饱和脂肪酸(SFA>总脂肪酸的55%)
  • 乳脂/黄油、可可脂
  • 蔗糖(重量占30%-50%)
  • 胆固醇(1-1.25%)
  • 巧克力源(0.5%)*

参考资料:

  1. 番茄汁番茄红素对大鼠肝脏脂肪变性的影响。j Nutr Biochem,2013年。24(11):P。1870-81
  2. 高,Q,等,动脉粥样硬化饮食加剧了小鼠缺乏谷胱甘肽过氧化物酶结肠炎。炎症肠Dis,2010年。16(12):P。2043-54
  3. Lichtman,A.H.,等,高脂血症和动脉粥样硬化病变的发展,低密度脂蛋白受体缺乏的小鼠,喂食定义半纯化饮食与不含胆酸。Arteroscler Thromb VASc Biol,1999年。19(8):P。1938-44年。
  4. 慢性精神应激和致动脉粥样硬化饮食对小鼠主动脉免疫炎症环境的影响。BrainBehav Immun,2011年。25(8):P。1649-57
  5. Nishina,P.m.,等,动物和植物来源的饮食脂肪对C57BL/6J小鼠因饮食引起的脂肪条纹损害的影响。j Lipid RES,1993年。34(8):P。1413-22
  6. Nishina,P.m.,等,9种近交系小鼠动脉粥样硬化及血浆和肝脏脂质。脂质,1993年。28(7):P。599-605
  7. 月,P,等,增强CD 36空小鼠肝脏载脂蛋白A-I分泌及胆固醇和磷脂的外周流出。PLOS One,2010年。5(3):P。E 9906
  8. Nishina,下午,J.Verstuyft,B.Paigen,合成低脂和高脂肪饮食,用于研究小鼠动脉粥样硬化。j Lipid RES,1990年。31(5):P。859-69

*胆酸钠或胆酸有助胆固醇和脂肪的吸收,并可透过胆汁酸合成减少胆固醇的排出。然而,如果你的研究不想包括胆酸盐的来源,没有胆酸盐的饮食是可用的。看见TD.96121为了纯正的饮食TD.94059混合饮食。请与我们联系,了解其他选项。

Wild type mice and rats generally are resistant to atherosclerosis, requiring more extreme dietary manipulation to modify lipoprotein profiles and develop mild atherosclerosis (foam cells, fatty streaks). Modern formulations are made completely of purified ingredients because this more refined approach has been reported to decrease the incidence of gallstones and liver damage associated with less refined and more traditional dietary approaches. To induce mild atherosclerosis in wild type animals, the “Western” purified diet can be modified to increase cholesterol (1-1.25%) and add a bile salt such as sodium cholate or cholic acid. Contact us for more information, modifications, or possible control diets.
Examples of purified high fat diets with added cholesterol and cholate source*:

  • TD.02028    21% milkfat (1.25% cholesterol, 0.5% cholic acid)
  • TD.09237    15% milkfat diet (1% cholesterol, 0.5% sodium cholate)

Examples of purified high fat diets with added cholesterol (without cholate source):

  • TD.96121    21% milkfat (1.25% cholesterol)

Research Use:
Induce hypercholesterolemia and mild atherosclerosis (foam cells, fatty streaks) primarily in wild type mice and rats.
Will not promote obesity.
Key dietary features:

  • High fat diet (15-20% by weight; 34 – 45% kcal from fat)
  • Saturated fatty acids (SFA >55% of total fatty acids)
  • Milkfat/butterfat, cocoa butter
  • Sucrose (30-50% by weight)
  • Cholesterol (1 – 1.25%)
  • Cholate source (0.5%)*

References:

  1. Bernal, C., et al., Lipid biomarkers and metabolic effects of lycopene from tomato juice on liver of rats with induced hepatic steatosis. J Nutr Biochem, 2013. 24(11): p. 1870-81.
  2. Gao, Q., et al., Atherogenic diets exacerbate colitis in mice deficient in glutathione peroxidase. Inflamm Bowel Dis, 2010. 16(12): p. 2043-54.
  3. Lichtman, A.H., et al., Hyperlipidemia and atherosclerotic lesion development in LDL receptor-deficient mice fed defined semipurified diets with and without cholate. Arterioscler Thromb Vasc Biol, 1999. 19(8): p. 1938-44.
  4. Marcondes, M.C., et al., Effects of chronic mental stress and atherogenic diet on the immune inflammatory environment in mouse aorta. Brain Behav Immun, 2011. 25(8): p. 1649-57.
  5. Nishina, P.M., et al., Effects of dietary fats from animal and plant sources on diet-induced fatty streak lesions in C57BL/6J mice. J Lipid Res, 1993. 34(8): p. 1413-22.
  6. Nishina, P.M., et al., Atherosclerosis and plasma and liver lipids in nine inbred strains of mice. Lipids, 1993. 28(7): p. 599-605.
  7. Yue, P., et al., Enhanced hepatic apoA-I secretion and peripheral efflux of cholesterol and phospholipid in CD36 null mice. PLoS One, 2010. 5(3): p. e9906.
  8. Nishina, P.M., J. Verstuyft, and B. Paigen, Synthetic low and high fat diets for the study of atherosclerosis in the mouse. J Lipid Res, 1990. 31(5): p. 859-69.

*Sodium cholate or cholic acid aid cholesterol and fat absorption and reduce cholesterol disposal via bile acid synthesis. However, if including a cholate source is not desired for your research, diets without cholate are available. See TD.96121 for a purified diet and TD.94059 for a hybrid diet. Contact us for additional options.

harlan teklad官网 动物饲料 TD.88137调整卡路里饮食 TD.1088545%脂肪KCAL饮食

“Western” style diets are fed to genetically-modified cardiovascular models, such as Apoe and Ldlr deficient mice, to accelerate and enhance hypercholesterolemia and plaque formation and to elicit phenotypes commonly associated with metabolic syndrome. Within the atherogenic literature, a “Western” diet typically is described as a purified rodent diet with 20-23% milkfat/butterfat, 0.2% total cholesterol, and 34% sucrose by weight. TD.88137 is an example of a “Western” style diet that was originally designed to characterize and enhance atherosclerosis development in a newly generated Apoe-deficient mouse model. Contact us for more information about “Western” style diets, modifications, or possible control diets.
Examples:

  • TD.88137    Adjusted calories diet (42% from fat, 0.2% total cholesterol)
  • TD.10885    45% fat Kcal diet (0.2% total cholesterol)

Research use:
Accelerated hypercholesterolemia and plaque formation in genetically-modified models, such as Apoe and Ldlr deficient mice.
Used for diet-induced obesity in a variety of rodent models.
Key dietary features:

  • High Fat Diet (20-23% by weight; 40 – 45% kcal from fat)
  • Saturated fatty acids (SFA >60% of total fatty acids)
  • Milkfat/butterfat
  • Sucrose (34% by weight)
  • Cholesterol (0.2% total)

References:

  1. Febbraio, M., et al., Targeted disruption of the class B scavenger receptor CD36 protects against atherosclerotic lesion development in mice. J Clin Invest, 2000. 105(8): p. 1049-56.
  2. Huszar, D., et al., Increased LDL cholesterol and atherosclerosis in LDL receptor-deficient mice with attenuated expression of scavenger receptor B1. Arterioscler Thromb Vasc Biol, 2000. 20(4): p. 1068-73.
  3. Nakashima, Y., et al., ApoE-deficient mice develop lesions of all phases of atherosclerosis throughout the arterial tree. Arterioscler Thromb, 1994. 14(1): p. 133-40.
  4. Nakashima, Y., et al., Upregulation of VCAM-1 and ICAM-1 at atherosclerosis-prone sites on the endothelium in the ApoE-deficient mouse. Arterioscler Thromb Vasc Biol, 1998. 18(5): p. 842-51.
  5. Plump, A.S., et al., Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells. Cell, 1992. 71(2): p. 343-53.
  6. Towler, D.A., et al., Diet-induced diabetes activates an osteogenic gene regulatory program in the aortas of low density lipoprotein receptor-deficient mice. J Biol Chem, 1998. 273(46): p. 30427-34.
  7. Tsuchiya, K., et al., FoxOs integrate pleiotropic actions of insulin in vascular endothelium to protect mice from atherosclerosis. Cell Metab, 2012. 15(3): p. 372-81.

harlan teklad官网 动物饲料氯化钠高盐TD.92012 TD.92034 TD.96208 NaCl调节饲料

NaCl调节(天然成分)

harlan teklad官网 动物饲料氯化钠高盐TD.92012 TD.92034 TD.96208 NaCl调节饲料

玉米、小麦、豆粕等天然成分的钠含量较低。因此,这些成分可以用来制造一种缺乏钠的基础饮食。在这一基础日粮中,可以添加各种量的氯化钠盐(NaCl),其他成分也可以稍加调整,以保持相对稳定的营养状况(除钠和氯化物外)。下面是一系列受欢迎的调整NaCl饮食的例子。欲了解更多信息,请与我们联系。
公式实例
添加NaCl(%) 大约。NA(%) 无染料 红*染料 橙*染料 蓝*染料
NA缺乏 0.01-0.02 TD.90228 TD.08290
可能的对照日粮:0.05%Na(0.1%NaCl)符合EST。最低钠需要量典型的啮齿动物日粮中含0.2%~0.4%Na(~0.5%-1%NaCl).
0.1 0.05 TD.94268 TD.07334
0.49 0.2 TD.96208 TD.110765
1 0.4 TD.90229
用于研究啮齿类动物摄入过量钠的影响的饮食。
2 0.8 TD.95078 TD.130345
4 1.6 TD.92034 TD.110078 TD.03095
8 3.2 TD.92012 TD.03142
*将这些水溶性食物染料加入天然成分的饮食中,可提供轻微的色泽。在较高的包合率下可以获得更强烈的颜色。
向营养师询问额外的盐浓度或颜色选择。
这些饮食是以谷物为基础的,没有动物来源的成分,并且背景钠含量约为。0.01-0.02%,背景氯含量约为0.01-0.02%.0.06-0.07%。日粮的营养成分为:蛋白质约19%,脂肪5%,粗纤维3%,钙0.86%,磷0.64%,钾0.72%,镁0.15%。
食盐调节后的饲料通常喂给Dahl盐敏感/耐盐(Rapp)近交系大鼠.这些老鼠传统饮食7034(0.12%NaCl)在最大安全生产设施内。

NaCl adjusted (natural ingredient) | Envigo

The sodium content of natural ingredients such as corn, wheat, and soybean meal is low. Thus, these ingredients can be used to create a base diet that is sodium deficient. To this base diet, various amounts of sodium chloride salt (NaCl) can be added, and other ingredients adjusted slightly to maintain a relatively constant nutrient profile (with the exception of sodium and chloride). Below are examples from a popular series of adjusted NaCl diets. Contact us for more information.
Formula examples
Added NaCl (%) Approx. Na (%) no dye red* dye orange* dye blue* dye
Na deficient 0.01-0.02 TD.90228 TD.08290
Possible control diets: 0.05% Na (0.1% NaCl) meets est. minimum Na requirement. Typical rodent diets contain 0.2%-0.4% Na (~0.5-1% NaCl).
0.1 0.05 TD.94268 TD.07334
0.49 0.2 TD.96208 TD.110765
1 0.4 TD.90229
Diets for studies that look at effects of excess sodium consumption in rodents.
2 0.8 TD.95078 TD.130345
4 1.6 TD.92034 TD.110078 TD.03095
8 3.2 TD.92012 TD.03142
* When added to natural ingredient diets, these water soluble food dyes offer a slight color tint. More intense color can be achieved at higher inclusion rates.
Ask a nutritionist about additional salt concentrations or color options.
These diets are grain-based, with no animal derived ingredients, and have a background sodium content of approx. 0.01-0.02% and a background chloride content of approx. 0.06-0.07%. The selected nutrient content of the diets are as follows: approximately 19% protein, 5% fat, 3% crude fiber, 0.86% Ca, 0.64% P, 0.72% K, and 0.15% Mg.
NaCl adjusted diets are often fed to dahl salt-sensitive/resistant (rapp) inbred rats. These rats are maintained on Teklad traditional diet 7034 (0.12% NaCl) within maximum security production facilities.

harlan teklad动物饲料官网 TD.88137 饮食诱导肥胖(DIO) Adjusted calories diet (42% from fat)

饮食诱导肥胖Envigo

harlan teklad动物饲料官网 TD.88137 饮食诱导肥胖(DIO) Adjusted calories diet (42% from fat)

用于诱导肥胖和肥胖相关并发症(如糖尿病和代谢综合征)的纯化高脂饮食通常有40-60%的能量来源于脂肪。下面的饮食表总结了一些特克拉德定制研究饮食的相关饮食特征,这些研究饮食通常用于啮齿类动物模型。
泰克乐还为其他物种,包括猪、灵长类动物和狗创造高脂肪饮食。联系我们讨论使用这些饮食或更好地满足您的需要。
通常使用的饮食诱导肥胖(DIO)技术啮齿动物饮食中含有55-60%的热量来自脂肪。
饮食特征 TD.06414 备好 TD.93075 面团 TD.07011 球团
千卡/克 5.1 4.8
脂肪,%千卡 60 55
脂肪来源,
按重量计百分比
31%猪油
3%豆油
27.4%蔬菜酥油
1.6%玉米油
脂肪酸谱,
总脂肪百分比
37%饱和
47%单不饱和
16%多不饱和
28%饱和,30%反式
28%单不饱和(顺式)
14%多不饱和
蔗糖
按重量计百分比
12.1 9.6
注记 60F10S海报数据
与D 12492比较
反式脂肪
示例修改 TD.08500椰子油
TD.09766乳脂
成分匹配,
低脂控制饮食*
TD.06416(35%蔗糖)
TD.08806(11%蔗糖)
TD.93074(21%蔗糖)
TD.120651(7%蔗糖)
参考文献
大鼠

大鼠

*控制饮食可以通过几种方式来设计,这取决于研究人员相对于高脂肪饮食想要改变什么特征。这些只是几个例子。

通常使用的饮食诱导肥胖(DIO)技术啮齿动物饮食中含有40-45%的热量来自脂肪。
饮食特征 TD.06415 TD.08811 TD.88137 备好 TD.95217
千卡/克 4.6 4.7 4.5 4.3
脂肪,%千卡 45 45 42 40
脂肪来源,
按重量计百分比
19.5%猪油
3%豆油
21%乳脂
2%豆油
21%乳脂 10.6%蔬菜酥油
4%乳脂
4%豆油
脂肪酸谱,
总脂肪百分比
36%饱和
46%单不饱和
18%多不饱和
61%饱和
31%单不饱和
8%多不饱和
62%饱和
27%单不饱和
5%多不饱和
34%饱和,18%反式
29%单不饱和(顺式)
19%多不饱和
蔗糖
按重量计百分比
22.8 36.8 34.5 15.8
注记 与D 12451比较 45F30S海报数据 “西餐”
添加胆固醇
反式脂肪
示例修改 TD.110716乳脂
TD.10670无染料
TD.130784猪油
TD.120438无染料
TD.07201猪油
TD.00573椰子油,不含胆固醇
TD.09682蓝色染料
TD.07734绿色染料
成分匹配,
低脂控制饮食*
TD.06416(35%蔗糖)
TD.110675(18%蔗糖)
TD.120455(6%蔗糖,抗性淀粉)
TD.120724(14%蔗糖)
TD.05230(34%蔗糖)
TD.08485(12%蔗糖)
TD.06101(6%蔗糖)
参考文献
大鼠

大鼠

大鼠

大鼠
全塌

从脂肪中摄取55-60%卡路里的食物TD.06414TD.93075通常用于诱发啮齿动物肥胖。虽然与典型的人类脂肪摄入相比,这些饮食被认为是极端的,但在大多数啮齿类动物中,这些饮食能有效地启动快速增重。由于脂肪含量较高,碳水化合物的摄入空间较小,因此碳水化合物(特别是蔗糖)含量相对较低。如果你对高脂肪和高碳水化合物感兴趣,那就看看脂肪中含有40-45%卡路里的饮食(通常被称为西方饮食)。
随着脂肪水平的增加,球团的质量(耐久性)经常受到损害。一些高脂肪配方只有在非颗粒形式,或需要特定的碳水化合物,麦芽糊精,用于球团。根据使用的脂肪和碳水化合物来源,非颗粒形式可能是致密和碎屑,面团样,或糊状。虽然使用非颗粒饮食更具有挑战性,但许多研究人员仍在使用非颗粒饮食来建立饮食诱导的肥胖模型,因为这些研究人员怀疑,较软的饮食形式可能会促进肥胖的发展。
从脂肪中摄取40-45%卡路里的饮食,如TD.95217TD.88137TD.06415,和TD.08811,代表了另一种流行的饮食模式-诱发肥胖的工作。这些食物的蔗糖含量是高脂肪饮食的两倍或三倍。高水平的简单碳水化合物,如蔗糖和果糖,可能有助于促进高甘油三酯血症,胰岛素抵抗和脂肪肝。高蔗糖、高饱和或反式脂肪的饮食在肥胖和心血管领域常被称为“西方饮食”。一些“西方饮食”有进一步的修改脂肪酸剖面,甚至特定的维生素和矿物质调整,以更紧密地匹配西方饮食模式。有关特定脂肪酸的修改,请参阅脂肪/脂肪调节饮食一页。
许多用于诱导啮齿动物肥胖的饮食可以用于增强糖尿病相关表型,如胰岛素抵抗和葡萄糖不耐受。然而,空腹高血糖特征的糖尿病(葡萄糖>200 mg/dL)是罕见的饮食方法。预先喂食高脂饮食,诱导一定程度的肥胖和胰岛素抵抗,然后给予小剂量链脲佐菌素(STZ)可能是一个有效的方法,如果公开高血糖是需要。
除了不同类型的碳水化合物外,还有许多不同水平和类型的脂肪,从蔗糖(高精制,简单消化)到玉米淀粉(精制,但更复杂),再到抗性淀粉(精制,但不能完全消化)。一个非常基本的净化控制饮食将是AIN-93M (TD.94048) 或AIN-93g(TD.94045)AIN-93日粮中蔗糖含量在10%左右,脂肪来源于具有健康脂肪酸的大豆油。更多的控制特定DIO饮食的例子可以在上表中找到。
许多研究人员选择将高脂肪喂养的动物与食用天然成分谷物的动物(也称为标准饮食或周食)进行比较。这些饮食在营养来源和水平以及非营养因素(如植酸盐或植物雌激素)存在的情况下存在差异。根据您的主要比较,它可能适合作为您的对照/参考组谷物基础的饮食。然而,这样的比较限制了对饮食模式和特定饮食成分的推断。

Diet induced obesity | Envigo

Purified high fat diets used to induce obesity and obesity-related complications such as diabetes and metabolic syndrome typically have 40-60% of energy derived from fat. The diet tables below summarize relevant diet features for several Teklad custom research diets commonly used in rodent models.
Teklad also creates high-fat diets for other species, including pigs, primates, and dogs. Contact us to discuss the use of these diets or one that better meets your needs.
Commonly-used diet-induced obesity (DIO) Teklad rodent diets with 55-60% of calories from fat
Diet features TD.06414stocked TD.93075dough TD.07011pellet
Kcal/g 5.1 4.8
Fat, % Kcal 60 55
Fat Sources,
% by weight
31% lard
3% soybean oil
27.4% vegetable shortening
1.6% corn oil
Fatty acid profile,
% total fat
37% saturated
47% monounsaturated
16% polyunsaturated
28% saturated, 30% trans
28% monounsaturated (cis)
14% polyunsaturated (cis)
Sucrose,
% by weight
12.1 9.6
Notes 60F10S poster data
Compare to D12492
Trans fat
Example modifications TD.08500coconut oil
TD.09766 milk fat
Ingredient matched,
low fat control diets*
TD.06416 (35% sucrose)
TD.08806 (11% sucrose)
TD.93074 (21% sucrose)
TD.120651 (7% sucrose)
References Mouse
Rat
Mouse
Rat

*Control diets can be designed in several ways, depending on what features the researcher wants to modify relative to the high-fat diet. These are just a few examples.

Commonly-used diet-induced obesity (DIO) Teklad rodent diets with 40-45% of calories from fat
Diet features TD.06415 TD.08811 TD.88137stocked TD.95217
Kcal/g 4.6 4.7 4.5 4.3
Fat, % Kcal 45 45 42 40
Fat sources,
% by weight
19.5% lard
3% soybean oil
21% milk fat
2% soybean oil
21% milk fat 10.6% vegetable shortening
4% milk fat
4% soybean oil
Fatty acid profile,
% total fat
36% saturated
46% monounsaturated
18% polyunsaturated
61% saturated
31% monounsaturated
8% polyunsaturated
62% saturated
27% monounsaturated
5% polyunsaturated
34% saturated, 18% trans
29% monounsaturated (cis)
19% polyunsaturated (cis)
Sucrose,
% by weight
22.8 36.8 34.5 15.8
Notes Compare to D12451 45F30S poster data “Western Diet”
Cholesterol added
Trans fat
Example modifications TD.110716 milk fat
TD.10670 no dye
TD.130784 lard
TD.120438 no dye
TD.07201 lard
TD.00573 h-coconut oil, no cholesterol
TD.09682 blue dye
TD.07734 green dye
Ingredient matched,
low fat control diets*
TD.06416 (35% sucrose)
TD.110675 (18% sucrose)
TD.120455 (6% sucrose, resistant starch)
TD.120724 (14% sucrose)
TD.05230 (34% sucrose)
TD.08485 (12% sucrose)
TD.06101 (6% sucrose)
References Mouse
Rat
Mouse
Rat
Mouse
Rat
Mouse
Rat
Collapse All Tabs

Diets with 55-60% of calories from fat like TD.06414 and TD.93075 are commonly used for inducing obesity in rodents. While considered extreme compared to typical human fat consumption, these diets are effective in initiating rapid weight gain in most rodents. With higher fat content there is less room for carbohydrate, thus the carbohydrate (particularly sucrose) amount is relatively low compared to other obesity inducing diets. If you are interested in high fat and high carbohydrate, look at diets with 40-45% of calories from fat (often referred to as western diets).
As the fat level increases, pellet quality (durability) is often compromised. Some higher fat formulas are available only in non-pelleted form or require specific carbohydrate, maltodextrin, for pelleting. Depending on the fat and carbohydrate sources used, the non-pelleted form could be dense and crumbly, dough-like, or paste-like. Though a little more challenging to work with, non-pelleted diet is still used by many researchers for diet-induced obesity models as these researchers suspect the softer form may enhance obesity development.
Diets with 40-45% of calories from fat, like TD.95217TD.88137TD.06415, and TD.08811, represent another popular diet pattern for diet-induced obesity work. These diets have double or triple the amount of sucrose found in higher fat diets. High levels of simple carbohydrate like sucrose and fructose may help to promote hypertriglyceridemia, insulin resistance, and fatty liver. Diets with a pattern of high sucrose and high saturated or trans fat are often referred to as “Western Diets” in obesity and cardiovascular fields. Some “Western Diets” have further modifications to the fatty acid profile or even specific vitamin and minerals adjustments to be even more closely matched to a Western Diet pattern. For specific fatty acid modifications, see examples on our fat/lipid adjusted diets page.
Many of the same diets used for inducing obesity in rodents can be used to enhance diabetes related phenotypes like insulin resistance and glucose intolerance. However, fasting hyperglycemia characteristic of diabetes (glucose > 200 mg/dL) is uncommon with a diet only approach. Pre-feeding a high fat diet to induce a certain level of obesity and insulin resistance and then giving low-dose streptozotocin (STZ) may be an effective approach if overt hyperglycemia is desired.
There are many options with different levels and types of fat in addition to different types of carbohydrate ranging from sucrose (highly refined, simple digestion) to corn starch (refined, but more complex) to resistant starch (refined, but not fully digestible). A very basic purified control diet would be AIN-93M (TD.94048) or AIN-93G (TD.94045). AIN-93 diets have a moderate amount of sucrose at ~10%, and fat is from soybean oil with a healthy fatty acid profile. Additional examples of controls for specific DIO diets can be found in the above tables.
Many researchers choose to compare their high fat fed animals to animals fed a natural ingredient, grain-based diet (also referred to as standard diets or chow). These diets differ in the source and level of nutrients as well as in the presence of non-nutritive factors (such as phytates or phytoestrogens). Depending on what your main comparisons are, it may be suitable to have a grain-based diet as your control/reference group. However, making such comparisons limits inferences to dietary patterns versus a specific dietary component.